Ikegame Satoshi, Nagamatsu Yoshinori, Nagata Nobuhiko, Kazumi Yuko, Mitarai Satoshi, Iwasaki Yasunori, Harada Chika, Kumazoe Hiroyuki, Kawasaki Masayuki, Kajiki Akira
National Hospital Organization, Omuta National Hospital, Japan.
Intern Med. 2012;51(16):2203-7. doi: 10.2169/internalmedicine.51.7848. Epub 2012 Aug 15.
A 25-year-old woman with no underlying disease presented with a large fluid-filled cavitary lesion in the right lung. Mycobacterium celatum was isolated from the cavitary fluid, and treatment with ethambutol, rifampicin, and clarithromycin was initiated. After 4 months of treatment, right lower pulmonary lobectomy was performed. Histological examination confirmed M. celatum infection as well as concurrent congenital cystic adenomatoid malformation (CCAM). M. celatum has been implicated in opportunistic infections. This infection, however, was related to underlying CCAM, which resulted in a large cavitary lesion. CCAM diagnosed in adulthood is rare, and is made more challenging by an infectious complication.
一名无基础疾病的25岁女性因右肺出现一个充满液体的大空洞性病变而就诊。从空洞液中分离出塞拉分枝杆菌，并开始用乙胺丁醇、利福平及克拉霉素进行治疗。治疗4个月后，实施了右下肺叶切除术。组织学检查证实为塞拉分枝杆菌感染以及并发先天性囊性腺瘤样畸形（CCAM）。塞拉分枝杆菌与机会性感染有关。然而，此次感染与潜在的CCAM相关，后者导致了一个大的空洞性病变。成年期诊断出的CCAM很罕见，且因感染性并发症而更具挑战性。
