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[内脏外科中的冰冻切片诊断。肝脏、胆管和胰腺]

[Frozen section diagnostics in visceral surgery. Liver, bile ducts and pancreas].

作者信息

Mogler C, Flechtenmacher C, Schirmacher P, Bergmann F

机构信息

Pathologisches Institut, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 220/21, 69120, Heidelberg, Deutschland.

出版信息

Pathologe. 2012 Sep;33(5):413-23. doi: 10.1007/s00292-012-1602-z.

DOI:10.1007/s00292-012-1602-z
PMID:22892660
Abstract

Intraoperative examination of specimens from the liver, bile ducts, gallbladder and pancreas are widely used in routine fresh frozen section diagnostics. The main clinical requests focus on diagnosis of masses of unknown dignity as well as evaluation of surgical margins in oncological resections. In addition, assessment of organ quality for transplantation is also often required.

摘要

肝脏、胆管、胆囊和胰腺标本的术中检查在常规新鲜冰冻切片诊断中被广泛应用。主要临床需求集中在不明性质肿块的诊断以及肿瘤切除术中手术切缘的评估。此外,对移植器官质量的评估也经常需要。

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2
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本文引用的文献

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Additional resection of an intraoperative margin-positive proximal bile duct improves survival in patients with hilar cholangiocarcinoma.术中近端胆管切缘阳性的额外切除可改善肝门部胆管癌患者的生存。
Ann Surg. 2011 Nov;254(5):776-81; discussion 781-3. doi: 10.1097/SLA.0b013e3182368f85.
2
Presence of pancreatic intraepithelial neoplasia in the pancreatic transection margin does not influence outcome in patients with R0 resected pancreatic cancer.在 R0 切除的胰腺癌患者中,胰腺横断切缘存在胰腺上皮内瘤变并不影响预后。
Ann Surg Oncol. 2011 Nov;18(12):3493-9. doi: 10.1245/s10434-011-1745-9. Epub 2011 May 3.
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供体肝脏组织学——移植选择中的一项重要工具。
Langenbecks Arch Surg. 2015 Jul;400(5):551-7. doi: 10.1007/s00423-015-1298-7. Epub 2015 Mar 26.
Histopathologic and clinical subtypes of autoimmune pancreatitis: the honolulu consensus document.
自身免疫性胰腺炎的组织病理学和临床亚型:檀香山共识文件。
Pancreatology. 2010;10(6):664-72. doi: 10.1159/000318809. Epub 2011 Jan 18.
4
The pathologic classification of neuroendocrine tumors: a review of nomenclature, grading, and staging systems.神经内分泌肿瘤的病理学分类:命名法、分级和分期系统综述。
Pancreas. 2010 Aug;39(6):707-12. doi: 10.1097/MPA.0b013e3181ec124e.
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Practical issues for frozen section diagnosis in gastrointestinal and liver diseases.胃肠道和肝脏疾病冰冻切片诊断的实际问题。
J Gastrointestin Liver Dis. 2010 Jun;19(2):181-5.
6
Predictive value of frozen-section analysis in the histological assessment of steatosis before liver transplantation.肝移植前肝脂肪变性组织学评估中冰冻切片分析的预测价值。
Liver Transpl. 2009 Dec;15(12):1821-5. doi: 10.1002/lt.21948.
7
Clinical significance of frozen section analysis during resection of intraductal papillary mucinous neoplasm: should a positive pancreatic margin for adenoma or borderline lesion be resected additionally?导管内乳头状黏液性肿瘤切除术中冰冻切片分析的临床意义:腺瘤或交界性病变的胰腺切缘阳性时是否应进一步切除?
J Am Coll Surg. 2009 Nov;209(5):614-21. doi: 10.1016/j.jamcollsurg.2009.07.023. Epub 2009 Sep 19.
8
Clinical value of additional resection of a margin-positive proximal bile duct in hilar cholangiocarcinoma.肝门部胆管癌切缘阳性近端胆管附加切除的临床价值。
Surgery. 2010 Jan;147(1):49-56. doi: 10.1016/j.surg.2009.06.030. Epub 2009 Sep 20.
9
Hepatic steatosis in organ donors: disparity between surgery and histology?器官捐献者的肝脏脂肪变性:手术与组织学之间的差异?
Transplant Proc. 2009 Jul-Aug;41(6):2557-60. doi: 10.1016/j.transproceed.2009.06.121.
10
Influence of pre-operative diagnosis and frozen section on operative management of pancreatic cystic lesions.术前诊断和冰冻切片对胰腺囊性病变手术处理的影响。
HPB (Oxford). 2005;7(3):235-7. doi: 10.1080/13651820510037648.