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暴发性痤疮经泼尼松和氨苯砜成功治愈。

Acne fulminans successfully treated with prednisone and dapsone.

作者信息

Lages Rafael Bandeira, Bona Sebastião Honório, Silva Flávia Veríssimo Melo e, Gomes Andressa Karoline Lima, Campelo Viriato

机构信息

Medicine School, Federal University of Piaui, Teresina, Brazil.

出版信息

An Bras Dermatol. 2012 Jul-Aug;87(4):612-4. doi: 10.1590/s0365-05962012000400015.

DOI:10.1590/s0365-05962012000400015
PMID:22892777
Abstract

Acne fulminans is a rare condition and the most severe form of acne. It involves the sudden onset of febrile and multisystemic symptoms, with poor response to ordinary therapy in patients who previously had mild to moderate acne. It is characterized by hemorrhagic ulcerative crusting lesions on the face, chest and upper back. The authors report a case of acne fulminans that was successfully treated with oral prednisone and dapsone.

摘要

暴发性痤疮是一种罕见的疾病,也是痤疮最严重的形式。它表现为发热和多系统症状的突然发作,既往有轻度至中度痤疮的患者对普通治疗反应不佳。其特征是面部、胸部和上背部出现出血性溃疡性结痂病变。作者报告了一例用口服泼尼松和氨苯砜成功治疗的暴发性痤疮病例。

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Acne fulminans successfully treated with prednisone and dapsone.暴发性痤疮经泼尼松和氨苯砜成功治愈。
An Bras Dermatol. 2012 Jul-Aug;87(4):612-4. doi: 10.1590/s0365-05962012000400015.
2
A case of acne fulminans in a patient with ulcerative colitis successfully treated with prednisolone and diaminodiphenylsulfone: a literature review of acne fulminans, rosacea fulminans and neutrophilic dermatoses occurring in the setting of inflammatory bowel disease.一例暴发性痤疮患者在溃疡性结肠炎中成功地接受了泼尼松龙和二氨基二苯砜治疗:炎症性肠病背景下出现的暴发性痤疮、酒渣鼻样脓疱病和中性粒细胞皮肤病的文献复习。
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Acne fulminans and erythema nodosum during isotretinoin therapy responding to dapsone.异维A酸治疗期间出现暴发性痤疮和结节性红斑,对氨苯砜治疗有效。
Clin Exp Dermatol. 1997 Jan;22(1):26-7. doi: 10.1046/j.1365-2230.1997.1830600.x.
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Acne fulminans treated with isotretinoin and "pulse" corticosteroids.异维A酸和“脉冲式”皮质类固醇治疗暴发性痤疮。
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Acne fulminans: investigation of acute febrile ulcerative acne.暴发性痤疮:急性发热性溃疡性痤疮的研究
Arch Dermatol. 1977 Apr;113(4):444-9. doi: 10.1001/archderm.113.4.444.
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Clinical evidence for the role of a topical anti-inflammatory agent in comedonal acne: findings from a randomized study of dapsone gel 5% in combination with tazarotene cream 0.1% in patients with acne vulgaris.局部抗炎药在粉刺性痤疮中作用的临床证据:一项针对寻常痤疮患者的5%氨苯砜凝胶联合0.1%他扎罗汀乳膏的随机研究结果
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Pseudo-acne fulminans associated with oral isotretinoin.与口服异维A酸相关的暴发性假性痤疮。
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Pyoderma gangrenosum following isotretinoin therapy for acne nodulocystic.异维A酸治疗结节囊肿性痤疮后出现坏疽性脓皮病。
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Cohort study on the treatment with dapsone 5% gel of mild to moderate inflammatory acne of the face in women.5%氨苯砜凝胶治疗女性面部轻至中度炎性痤疮的队列研究
Skinmed. 2014 Jan-Feb;12(1):15-21.
10
Acne fulminans.暴发性痤疮
Am Fam Physician. 1989 Sep;40(3):135-9.

引用本文的文献

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Acne Conglobata: Understanding This Rare Form of Acne and Management Strategies.聚合性痤疮:了解这种罕见的痤疮形式及管理策略
Dermatol Ther (Heidelb). 2025 Aug 23. doi: 10.1007/s13555-025-01523-x.
2
Acne fulminans treatment: case report and literature review.暴发性痤疮的治疗:病例报告与文献综述
Front Med (Lausanne). 2024 Jul 30;11:1450666. doi: 10.3389/fmed.2024.1450666. eCollection 2024.
3
Isotretinoin-induced Acne Fulminans without Systemic Symptoms Treated Successfully with Oral Dapsone.口服氨苯砜成功治疗无全身症状的异维A酸诱发的暴发性痤疮
Acta Derm Venereol. 2020 Jan 23;100(1):adv00036. doi: 10.2340/00015555-3354.
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Acne fulminans.暴发性痤疮
An Bras Dermatol. 2017;92(5 Suppl 1):8-10. doi: 10.1590/abd1806-4841.20176546.
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Successful Treatment of Facial Acne Fulminans: Antimicrobial Agents and Oral Prednisolone as Promising Regimes.暴发性面部痤疮的成功治疗:抗菌药物和口服泼尼松龙作为有前景的治疗方案。
Case Rep Dermatol Med. 2017;2017:7092910. doi: 10.1155/2017/7092910. Epub 2017 Mar 27.
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When strength turns into disease: acne fulminans in a bodybuilder.当力量转化为疾病:一名健美运动员身上的暴发性痤疮。
An Bras Dermatol. 2016 Sep-Oct;91(5):706. doi: 10.1590/abd1806-4841.20165345.