Hondappanavar Anil, Sodhi Kushaljit Singh, Dutta Sourabh, Saxena Akshay Kumar, Khandelwal Niranjan
Department of Radiodiagnosis, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India.
Pediatr Cardiol. 2013 Feb;34(2):364-9. doi: 10.1007/s00246-012-0464-8. Epub 2012 Aug 15.
The objective of this study was to measure intima-media thickness (IMT) of the abdominal aortic (aIMT) and common carotid (cIMT) arteries in normal term newborns. We measured aIMT and cIMT using high-resolution ultrasonography in 100 normal term newborns during the first 4 days of life. Mean abdominal aIMT and cIMT values of term newborns were 0.51 ± 0.041 mm (n = 100) and 0.37 ± 0.054 mm (n = 100), respectively. Maximum and minimum aIMT and cIMT values of term newborns were 0.58 and 0.42 mm and 0.47 and 0.32 mm, respectively. The intraobserver intrasubject correlation coefficients for aIMT, right cIMT, and left cIMT were 0.89, 0.91, and 0.92, respectively (coefficient of variation = 5 %). The study provides data for normal aIMT and cIMT values in normal term newborns. By establishing normal values, we can further study the aetiopathogenesis of various possible intrauterine risk factors in premature atherosclerosis in normal or intrauterine growth-retarded newborns.
本研究的目的是测量足月新生儿腹主动脉(aIMT)和颈总动脉(cIMT)的内膜中层厚度。我们在出生后4天内,使用高分辨率超声对100名足月新生儿测量了aIMT和cIMT。足月新生儿的平均腹主动脉aIMT和cIMT值分别为0.51±0.041毫米(n = 100)和0.37±0.054毫米(n = 100)。足月新生儿的aIMT和cIMT的最大值和最小值分别为0.58和0.42毫米以及0.47和0.32毫米。aIMT、右侧cIMT和左侧cIMT的观察者内受试者间相关系数分别为0.89、0.91和0.92(变异系数 = 5%)。该研究提供了足月新生儿正常aIMT和cIMT值的数据。通过确定正常值,我们可以进一步研究正常或宫内生长受限新生儿早产动脉粥样硬化中各种可能的宫内危险因素的病因发病机制。