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使用台式血液浓缩器装置对浓缩红细胞和新鲜冰冻血浆中的钠、葡萄糖、钾及渗透压进行调节。

Modification of sodium, glucose, potassium, and osmolarity in packed red blood cells and fresh frozen plasma using a desktop hemoconcentrator setup.

作者信息

Striker Carrie Whittaker, Woldorf Stacia, Holt David

机构信息

Department of Cardiothoracic Surgery, Children's Mercy Hospitals and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA.

出版信息

J Extra Corpor Technol. 2012 Jun;44(2):60-5.

Abstract

Massive transfusion with packed blood cells (PRBCs) or fresh frozen plasma (FFP) can result in dangerous complications including stroke, kidney failure, and cardiac arrest. A simple, bench top technique using a hemoconcentrator and dialysate solution is described to correct critical values of sodium, glucose, potassium, and osmolarity in PRBCs and FFP. Sodium, glucose, and osmolarity were corrected to normal or near normal values. Elevated potassium was reduced by 65%, but not completely normalized. A simple, bench top method for correcting dangerous abnormalities with PRBCs and FFP can be used to improve the safety of massive blood transfusion.

摘要

大量输注浓缩红细胞(PRBCs)或新鲜冰冻血浆(FFP)可能会导致包括中风、肾衰竭和心脏骤停在内的危险并发症。本文描述了一种使用血液浓缩器和透析液的简单台式技术,用于纠正PRBCs和FFP中的钠、葡萄糖、钾和渗透压的临界值。钠、葡萄糖和渗透压被纠正至正常或接近正常水平。升高的钾降低了65%,但未完全恢复正常。一种用于纠正PRBCs和FFP中危险异常的简单台式方法可用于提高大量输血的安全性。

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本文引用的文献

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Intraoperative washing of long-stored packed red blood cells by using an autotransfusion device prevents hyperkalemia.
Anesth Analg. 2002 Aug;95(2):324-5, table of contents. doi: 10.1097/00000539-200208000-00015.

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