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[葡萄球菌食物中毒与耐甲氧西林金黄色葡萄球菌肠炎]

[Staphylococcal food poisoning and MRSA enterocolitis].

作者信息

Okuyama Yusuke, Yoshida Norimasa

机构信息

Department of Gastroenterology, Kyoto First Red Cross Hospital.

出版信息

Nihon Rinsho. 2012 Aug;70(8):1362-5.

PMID:22894073
Abstract

Staphylococcal food poisoning is a gastrointestinal illness. It is caused by eating foods contaminated with enterotoxins produced by Staphylococcus aureus. The enterotoxins are fast acting, sometimes causing illness within one to six hours. Patients typically experience nausea, vomiting, stomach cramps, and diarrhea. Diagnosis of staphylococcal food poisoning is generally based only on the symptoms of patients. The treatments for these patients are rest and plenty of fluids. Antibiotics are not useful in treating this illness. On the other hand, methicillin resistant Staphylococcus aureus (MRSA) enteritis and colitis caused by microbial substitution with administration of antibiotics is aggressive and sick with severe diarrhea. The treatment of those patients are as follows; antibiotics now in use are stopped and oral administration of vancomycin is started as soon as possible.

摘要

葡萄球菌食物中毒是一种胃肠道疾病。它是由食用被金黄色葡萄球菌产生的肠毒素污染的食物引起的。肠毒素作用迅速,有时在一到六小时内就会引发疾病。患者通常会出现恶心、呕吐、胃痉挛和腹泻。葡萄球菌食物中毒的诊断通常仅基于患者的症状。这些患者的治疗方法是休息并大量补充液体。抗生素对治疗这种疾病没有作用。另一方面,由抗生素使用导致微生物替代引起的耐甲氧西林金黄色葡萄球菌(MRSA)肠炎和结肠炎病情严重且伴有严重腹泻。这些患者的治疗方法如下:停用目前正在使用的抗生素,并尽快开始口服万古霉素。

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Pathway based therapeutic targets identification and development of an interactive database CampyNIBase of Campylobacter jejuni RM1221 through non-redundant protein dataset.基于通路的治疗靶点鉴定和开发空肠弯曲菌 RM1221 的交互式数据库 CampyNIBase 通过非冗余蛋白质数据集。
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