Masuda H, Yamada T, Nagamatsu H, Nagahama K, Negishi T
Department of Urology, Kasukabe Municipal Hospital.
Hinyokika Kiyo. 1992 Dec;38(12):1425-8.
Recently, the frequency of methicillin resistant Staphylococcus aureus (MRSA) infection has been increasing. We experienced a case of postoperative enterocolitis due to MRSA. The patient was an 81-year-old male with benign prostatic hypertrophy. Urine leakage from the penrose drain tube appeared 1 day after suprapubic prostatectomy. We had used intravenous infusion of antibiotic agents including cefodizine (CDZM), imipenem (IPM/CS) and cefmetazol (CMZ). He developed severe diarrhea, high fever, oliguria, leg edema and ascites 24 days after the operation. MRSA was detected from his feces. Toxic shock syndrome toxin-I (TSST-I) was produced by this bacteria the coagulase type of which was type II. The patient was treated with oral vancomycin (1 g/day), to which this bacteria showed sensitivity and the patient showed, improvement, including symptoms, leucocytosis and serum CRP level 12 days after administration of vancomycin.
最近，耐甲氧西林金黄色葡萄球菌（MRSA）感染的频率一直在增加。我们遇到了一例因MRSA引起的术后小肠结肠炎病例。患者是一名81岁男性，患有良性前列腺增生。耻骨上前列腺切除术后1天，彭罗斯引流管出现尿液渗漏。我们曾静脉输注包括头孢地嗪（CDZM）、亚胺培南（IPM/CS）和头孢美唑（CMZ）在内的抗生素。术后24天，他出现了严重腹泻、高热、少尿、腿部水肿和腹水。从他的粪便中检测出了MRSA。这种凝固酶类型为II型的细菌产生了毒性休克综合征毒素-I（TSST-I）。患者接受了口服万古霉素（1克/天）治疗，该细菌对万古霉素敏感，在给予万古霉素12天后，患者的症状、白细胞增多和血清CRP水平等情况均有所改善。
