Rothbarth Joost, Verhoef C Kees, Poley Jan-Werner, Biermann Katharina, van Lanschot Jan J B, Wijnhoven Bas P L
Erasmus MC, Afd. Chirurgie, Rotterdam, the Netherlands.
Ned Tijdschr Geneeskd. 2012;156(33):A4549.
A submucosal oesophageal tumour consists of a submucosal oesophageal mass with normal overlying mucosa. Its broad differential diagnosis includes leiomyoma and gastro-intestinal stromal cell tumour. For a correct diagnosis and further management, an upper-gastrointestinal endoscopy and endosonography, together with a needle biopsy of the lesion for histology and for immunohistochemical analysis, are mandatory. Needle biopsies in tumours smaller than 2 cm are probably less reliable and in such cases, follow-up endoscopic ultrasonography is advised. We present two patients with submucosal oesophageal tumours and discuss their diagnostics and treatment plans.
黏膜下食管肿瘤由黏膜下食管肿物及上方正常黏膜组成。其广泛的鉴别诊断包括平滑肌瘤和胃肠道间质细胞瘤。为做出正确诊断并进行进一步处理,必须进行上消化道内镜检查和内镜超声检查,同时对病变进行针吸活检以进行组织学和免疫组化分析。对于小于2厘米的肿瘤,针吸活检可能不太可靠,在这种情况下,建议进行随访内镜超声检查。我们介绍两名黏膜下食管肿瘤患者,并讨论其诊断和治疗方案。