An esophageal SCC case which could be distinguished from non-neoplasia using magnifying endoscopy with NBI imaging.

In this case, narrow-band imaging helped to distinguish esophagitis. The case involved an 81-year-old female was being seen as an outpatient because of Gastroesophageal Reflux Disease (GERD) symptoms associated with an esophageal hiatal hernia. Endoscopy showed long reddish lesions on the posterior wall of the lower thoracic esophagus. Non-magnifying endoscopic images with white light initially suggested reflux esophagitis. Magnifying endoscopy with narrow-band imaging showed proliferation of intraepithelial papillary capillary loop-like vessels as well as irregular widening and narrowing of vessels, so the patient's condition was diagnosed as superficial esophageal cancer. Endoscopic submucosal dissection was carried out.