Hayden Richard E, Mullin David P, Patel Andrew K
Mayo Clinic, Phoenix, Arizona, USA.
Curr Opin Otolaryngol Head Neck Surg. 2012 Aug;20(4):231-6. doi: 10.1097/MOO.0b013e328355d0f3.
This article reviews literature pertaining to advances in the reconstruction of segmental mandibular defects in the context of an established standard of care, microvascular transfer of free osteocutaneous flaps.
Most literature reiterates established reconstructive techniques. Exceptions include the use of computer-assisted modeling to preoperatively design the excision of both the mandible and fibula segments and to produce a template for contouring the neomandible, the design of new flaps, distraction osteogenesis and techniques for dealing with osteonecrosis.
The microvascular transfer of free osteocutaneous flaps remains the standard of care, with the fibula flap the clear favorite. Review of the evolution of this flap for segmental mandibular reconstruction provides the bulk of the literature. Improvement on this standard of practice continues to be elusive, in large part because of the effects of associated radiation. Tissue engineering holds promise but no current practical application is available.
本文在既定的标准治疗方法——游离骨皮瓣微血管移植的背景下,回顾了有关节段性下颌骨缺损重建进展的文献。
大多数文献重申了既定的重建技术。例外情况包括使用计算机辅助建模在术前设计下颌骨和腓骨段的切除,并制作用于塑造新下颌骨轮廓的模板、新型皮瓣的设计、牵张成骨以及处理骨坏死的技术。
游离骨皮瓣微血管移植仍然是标准治疗方法,腓骨瓣是明显的首选。对该皮瓣用于节段性下颌骨重建的演变进行回顾构成了大部分文献。在很大程度上由于相关放疗的影响,对这种标准治疗方法的改进仍然难以实现。组织工程有前景,但目前尚无实际应用。