Xin D, Wu L, Wu D
Department of Ophthalmology, Guangdong Provincial People's Hospital, Guangzhou, China.
Yan Ke Xue Bao. 1990 Dec;6(3-4):80-3, 65.
In this study the pattern-reversal stimulation was used for analysing the clinical VEP in 27 cases (37 eyes) of ischemic optic neuropathy (ION), and combined uses of visual field (VF) and contrast sensitivity (CS) examinations were compared and observed with 3 kinds of spatial frequencies (60', 30', 15' check size), VEP in the eyes of ION displayed decrease in amplitude as a dominant manifestation accompanied by the slight increase of latency period. The abnormal latency and amplitude were 83.5% and 81.3% respectively. The decreased CS in the ION eyes was appeared mainly in the stimulation of middle and high frequencies or all frequency bands. There was a significant correlation between the VEP amplitude and CS in the patients with ION. The quadrant VF defect and bow-shaped scotoma were displayed in majority of the cases. Abnormal VEP was shown to be related to the central VF impaired. Among these patients, 7 cases (8 eyes) were followed up with VEP, however the VEP amplitude was shown decreasing somewhat compared with first exam. The results indicated that the ION was responsible for many visual function damages.
本研究采用图形翻转刺激分析27例（37只眼）缺血性视神经病变（ION）患者的临床视觉诱发电位（VEP），并比较观察了视野（VF）和对比敏感度（CS）检查联合应用3种空间频率（60′、30′、15′检查尺寸）时ION患者眼的情况，ION患者眼的VEP表现为以波幅降低为主，伴有潜伏期轻度延长。潜伏期和波幅异常率分别为83.5%和81.3%。ION患者眼的CS降低主要出现在中高频或全频段刺激时。ION患者的VEP波幅与CS之间存在显著相关性。大多数病例出现象限性视野缺损和弓形暗点。异常VEP与中心视野损害有关。其中7例（8只眼）患者进行了VEP随访，然而与首次检查相比，VEP波幅有所下降。结果表明，ION可导致多种视觉功能损害。
