WCU Biomodulation Major, Department of Agricultural Biotechnology, Seoul National University, Seoul 151-921, Republic of Korea.
J Med Entomol. 2012 Jul;49(4):876-85. doi: 10.1603/me11127.
In all triplicate tests of six plant essential oils and of vanillin mixtures, we corroborated strong insecticidal and repellent activities against adult Aedes aegypti (L.). Essential oils with potent toxic fumigant activities also exhibited repellency. Compared with N, N-diethyl-3-methylbenzamide, 5% of the essential oil concentrations of cassia, lemongrass, lemon eucalyptus, and xanthoxylum oils did not show repellent effects. However, a composition oflemongrass oil, xanthoxylum oil, and vanillin (1:3:1, vol:vol:wt) provided 270 min of complete protection time (CPT) compared with 247.5 min CPT with 15% N, N-diethyl-3-methylbenzamide. The CPT depended on concentration, presence ofvanillin, or on both factors. When we applied a mixture of lemongrass oil: xanthoxylum oil: vanillin (1:1:1, vol:vol:wt) to the Viscopearl formulation, or porous cellulose beads, it provided gradual release of volatile compounds, thus showing >90% of repellency for 2 h. The behavioral and electrophysiological approaches we drew upon in our current study demonstrated that plant essential oil mixtures combined with vanillin showed strong and durable repellency to the mosquito. We claim that such combinations of plant essential oils and vanillin found in current study propose a viable commercial product suitable for future application in protecting a person from mosquito bites.
在对六种植物精油和香草醛混合物进行的三次重复测试中，我们证实了它们对成蚊（埃及伊蚊）具有强烈的杀虫和驱避作用。具有强烈毒性熏蒸活性的精油也表现出驱避作用。与 N，N-二乙基-3-甲基苯甲酰胺相比，5%的肉桂、柠檬草、柠檬桉和花椒油的精油浓度没有表现出驱避效果。然而，由柠檬草油、花椒油和香草醛（1:3:1，体积比：体积比：重量比）组成的组合物提供了 270 分钟的完全保护时间（CPT），而 15%的 N，N-二乙基-3-甲基苯甲酰胺则提供了 247.5 分钟的 CPT。CPT 取决于浓度、香草醛的存在或这两个因素。当我们将柠檬草油：花椒油：香草醛（1:1:1，体积比：体积比：重量比）的混合物应用于 Viscopearl 制剂或多孔纤维素珠时，它提供了挥发性化合物的逐渐释放，从而表现出超过 90%的 2 小时驱避率。我们在当前研究中采用的行为和电生理方法表明，植物精油混合物与香草醛结合具有强烈和持久的驱蚊效果。我们声称，当前研究中发现的这种植物精油和香草醛的组合提出了一种可行的商业产品，适合未来用于保护人们免受蚊虫叮咬。
