Jeeva J B, Singh Megha
Biomedical Engineering Division, School of Biosciences and Biotechnology, V.I.T. University, Vellore-632014, India.
Electromagn Biol Med. 2012 Sep;31(3):204-12. doi: 10.3109/15368378.2012.700296.
Photon propagation through tissue phantoms, made of heart, adipose, and spleen tissues was simulated by Monte Carlo procedure. To detect the presence of deep-seated abnormalities, phantoms of heart with adipose and spleen tissues embedded into it were created and simulations were performed to scan the tissue surface with a source and four detector model. Profiles drawn showed variation in parameters such as backscattered intensity in regions where adipose and spleen tissues were embedded. This study shows that depending on the type of embedded tissue the backscattered fraction as measured at 2 mm from the input fiber is altered. This is enhanced for adipose and decreased for spleen tissue. This is not only shown in scanned profiles on the surface but also in constructed images.
通过蒙特卡罗方法模拟了光子在由心脏、脂肪和脾脏组织制成的组织模型中的传播。为了检测深层异常的存在,制作了嵌入脂肪和脾脏组织的心脏模型,并使用源和四探测器模型对组织表面进行扫描模拟。绘制的剖面图显示,在嵌入脂肪和脾脏组织的区域,诸如背向散射强度等参数存在变化。这项研究表明,根据嵌入组织的类型,在距输入光纤2毫米处测量的背向散射分数会发生改变。脂肪组织的背向散射分数增加,脾脏组织的背向散射分数降低。这不仅在表面扫描剖面图中得到显示,在构建的图像中也得到了体现。