Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway.
Acta Obstet Gynecol Scand. 2013 Jan;92(1):75-84. doi: 10.1111/j.1600-0412.2012.01528.x.
To evaluate the clinical use of ST analysis (STAN) for intrapartum monitoring of high-risk pregnancies.
Prospective observational study.
University hospital, Norway, 2004-2008.
Singleton pregnancies with a gestational age above 35(+6) weeks.
Analysis of maternal and neonatal outcomes for all deliveries according to the method of intrapartum monitoring.
Prevalence of cord metabolic acidosis (pH < 7.05, extracellular fluid base deficit (extracellular fluid) >12 mmol/L).
Of 23 203 deliveries, 6010 (25.9%) were monitored with STAN. Fetal blood sampling was performed in 146 (2.4%) of the 6010 cases. During the study period, the prevalence of cord metabolic acidosis and moderate cord acidosis (pH < 7.15) decreased in STAN-monitored deliveries from 1.4 to 0.3% (p = 0.01) and from 16.4 to 11.7% (p = 0.001), respectively. The prevalence of moderate and severe neonatal encephalopathy was 0.38%. In the birth population, the proportion of cesarean deliveries decreased from 10.1 to 8.8%. The risk of emergency cesarean section after STAN monitoring compared with those monitored with auscultation/cardiotocography was high (odds ratio 5.4, 95% confidence interval = 4.9-6.1) but remained stable during the study period.
ST analysis is a useful tool for identification of fetuses at risk of intrapartum hypoxia. Despite the restricted use of fetal blood sampling, we found a low proportion of cord metabolic acidosis and newborn morbidity.
评估 ST 分析(STAN)在高危妊娠产时监测中的临床应用。
前瞻性观察性研究。
挪威大学医院,2004-2008 年。
孕周大于 35(+6)周的单胎妊娠。
根据产时监测方法分析所有分娩的母婴结局。
脐带代谢性酸中毒(pH<7.05,细胞外液碱剩余(extracellular fluid)>12mmol/L)的发生率。
在 23203 例分娩中,6010 例(25.9%)接受 STAN 监测。在这 6010 例患者中,有 146 例(2.4%)进行了胎儿血样采集。在研究期间,STAN 监测分娩中脐带代谢性酸中毒和中度脐带酸中毒(pH<7.15)的发生率从 1.4%降至 0.3%(p=0.01),从 16.4%降至 11.7%(p=0.001)。中度和重度新生儿脑病的发生率为 0.38%。在分娩人群中,剖宫产率从 10.1%降至 8.8%。与听诊/胎心监护相比,STAN 监测后的紧急剖宫产风险较高(优势比 5.4,95%置信区间=4.9-6.1),但在研究期间保持稳定。
ST 分析是识别产时缺氧胎儿的有用工具。尽管胎儿血样采集的应用受限,但我们发现脐带代谢性酸中毒和新生儿发病率的比例较低。