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ST分析在临床实践中的局限性:三例产时代谢性酸中毒病例

Limitations of ST analysis in clinical practice: three cases of intrapartum metabolic acidosis.

作者信息

Westerhuis M E M H, Kwee A, van Ginkel A A, Drogtrop A P, Gyselaers W J A, Visser G H A

机构信息

Department of Obstetrics and Gynaecology, University Medical Centre Utrecht, Wilhelmina Children's Hospital, Utrecht, The Netherlands.

出版信息

BJOG. 2007 Oct;114(10):1194-201. doi: 10.1111/j.1471-0528.2007.01236.x. Epub 2007 May 15.

Abstract

OBJECTIVE

To examine detailed intrapartum events in cases of neonatal metabolic acidosis despite monitoring using STAN (cardiotocography [CTG] plus ST waveform analysis of fetal electrocardiogram [ECG]).

DESIGN

Retrospective case review.

SETTING

High-risk pregnancies monitored by STAN.

METHODS

Case note review was performed in newborns with metabolic acidosis where no significant ST changes in the fetal ECG occurred prior to birth.

MAIN OUTCOME MEASURES

Metabolic acidosis.

RESULTS

Detailed review of three cases identified poor signal quality, difficulties in CTG interpretation, failure to comply with STAN clinical guidelines and deterioration of the CTG without ECG alert as the leading causes of these adverse outcomes.

CONCLUSIONS

The cases illustrate some of the pitfalls associated with the clinical application of the STAN technology which prevent severe metabolic acidosis being eradicated completely. It may be useful to expand the STAN guidelines protocol towards the identification of exceptional clinical situations, such as in our cases, and towards appropriate additional interventions, as this may lead to a further reduction in adverse neonatal outcomes.

摘要

目的

尽管使用STAN(产时胎心监护[CTG]加胎儿心电图[ECG]的ST段波形分析)进行监测,仍要检查新生儿代谢性酸中毒病例中的详细分娩期事件。

设计

回顾性病例审查。

背景

由STAN监测的高危妊娠。

方法

对出生前胎儿心电图未出现明显ST段变化的代谢性酸中毒新生儿进行病例记录审查。

主要观察指标

代谢性酸中毒。

结果

对三例病例的详细审查发现,信号质量差、CTG解读困难、未遵守STAN临床指南以及CTG恶化但无ECG警报是这些不良结局的主要原因。

结论

这些病例说明了与STAN技术临床应用相关的一些陷阱,这些陷阱阻碍了严重代谢性酸中毒的完全消除。扩大STAN指南方案以识别特殊临床情况(如我们病例中的情况)并采取适当的额外干预措施可能是有用的,因为这可能会进一步降低新生儿不良结局。

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