Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada.
JACC Cardiovasc Imaging. 2012 Aug;5(8):829-36. doi: 10.1016/j.jcmg.2011.12.026.
Dual-energy computed tomography (DECT) has recently been introduced for clinical use. One potential application of DECT is myocardial perfusion imaging through the significant reduction of beam-hardening artifacts by using monochromatic image reconstruction; analysis of these images can improve the accuracy of quantitative measurement of myocardial perfusion. Single-source DECT enabled by rapid switching between the low and high tube potentials (kV) can minimize misregistration of the high and low kV projection datasets from cardiac motion. We have recently implemented prospective electrocardiography-triggering capability in our rapid kV-switching computed tomography (CT) scanner to reduce the high effective dose from a quantitative CT myocardial perfusion imaging study with DECT. Our initial investigation suggests that prospectively electrocardiography-triggered rapid kV-switching DECT can eliminate beam hardening and provide a more reproducible myocardial perfusion measurement compared with the traditional single-energy CT protocol.
双能计算机断层扫描（DECT）最近已被引入临床应用。DECT 的一个潜在应用是通过使用单能量图像重建显著减少射束硬化伪影来进行心肌灌注成像；对这些图像进行分析可以提高心肌灌注定量测量的准确性。通过在高低管电压（kV）之间快速切换实现的单源 DECT 可以最小化由于心脏运动导致的高低 kV 投影数据集的配准错误。我们最近在我们的快速 kV 切换 CT（CT）扫描仪中实现了前瞻性心电图触发功能，以降低使用 DECT 进行定量 CT 心肌灌注成像研究的高有效剂量。我们的初步研究表明，与传统的单能量 CT 方案相比，前瞻性心电图触发的快速 kV 切换 DECT 可以消除射束硬化并提供更可重复的心肌灌注测量。
