Al-Homood Ibrahim A
College of Medicine, Imam Muhammad Ibn Saud Islamic University, P.O. Box 75227, Riyadh 11578, Saudi Arabia.
ISRN Rheumatol. 2012;2012:428269. doi: 10.5402/2012/428269. Epub 2012 Jul 30.
Thrombosis is a well-known clinical entity in systemic lupus erythematosus (SLE), and it is multifactorial. The most important risk factor is the presence of antiphospholipid antibodies (APLAs). However, approximately 40% of adults with SLE who are negative for APL A are diagnosed with thrombosis, indicating the importance of other risk factors. Thus, the thrombosis risk factors should be evaluated extensively and regularly and treated aggressively in every patient with systemic lupus erythematosus.
血栓形成是系统性红斑狼疮(SLE)中一种众所周知的临床病症,且其病因是多方面的。最重要的危险因素是抗磷脂抗体(APLAs)的存在。然而,约40%的APL A检测呈阴性的SLE成年患者被诊断为血栓形成,这表明其他危险因素的重要性。因此,对于每一位系统性红斑狼疮患者,都应广泛且定期地评估血栓形成危险因素,并积极进行治疗。