Zhou Ping, Huang Wei, Chu Xing, Du Liang-Feng, Li Jian-Ping, Zhang Chun
Department of General Surgery, the Third Affiliated Hospital to Nantong University, Wuxi, China.
Asian Pac J Cancer Prev. 2012;13(5):1949-52. doi: 10.7314/apjcp.2012.13.5.1949.
The aim of this meta-analysis is to evaluate associations between LTA-252 A>G and breast cancer (BC).
Electronic searches of several databases were conducted for all online publications. A total of 7 studies involving 4,625 BC patients and 4,373 controls were identified.
This meta-analysis showed no significant association between the LTA-252 A>G polymorphism and BC in overall or Caucasian populations. However, a positive association was found limited to Asian populations.
Although there was no significant association found between the LTA-252 A>G polymorphism and BC overall, a positive association was found in Asian populations.
本荟萃分析旨在评估LTA - 252 A>G与乳腺癌（BC）之间的关联。
对多个数据库进行电子检索以查找所有在线出版物。共纳入7项研究，涉及4625例BC患者和4373例对照。
本荟萃分析表明，在总体人群或白种人群中，LTA - 252 A>G多态性与BC之间无显著关联。然而，仅在亚洲人群中发现了正相关。
虽然总体上LTA - 252 A>G多态性与BC之间未发现显著关联，但在亚洲人群中发现了正相关。
