Department of Internal Medicine, School of Medicine, CHA University, Korea.
Thromb Res. 2012 Oct;130(4):e199-202. doi: 10.1016/j.thromres.2012.07.019. Epub 2012 Aug 15.
There have been conflicting results on seasonal variation in the occurrence of venous thromboembolism (VTE). It also has never been studied in Asian population. To address these issues, we investigated seasonal changes of the incidence of VTE in Korean population using 1,495 patients with VTE between January 2001 and December 2010. VTE occurred most frequently in the winter and least frequently in the summer (χ2=11.83, P=0.008). In the subset analyses, the same trend was shown in the PE±DVT group, the unprovoked VTE group, and the VTE without malignancy group. The monthly occurrence rate peaked in December and was at its lowest in July (P=0.004). In conclusion, our study provides evidence that there is an increased risk for VTE in Korean population in the winter season.
静脉血栓栓塞症（VTE）的发生存在季节性变化，但结果存在争议。这在亚洲人群中从未被研究过。为了解决这些问题，我们调查了韩国人群中 VTE 发生率的季节性变化，纳入了 2001 年 1 月至 2010 年 12 月期间的 1495 例 VTE 患者。VTE 最常发生在冬季，最少发生在夏季（χ2=11.83，P=0.008）。在亚组分析中，PE±DVT 组、无诱因 VTE 组和无恶性肿瘤 VTE 组也显示出相同的趋势。每月发生率在 12 月最高，7 月最低（P=0.004）。总之，我们的研究提供了证据，表明韩国人群在冬季 VTE 的风险增加。
