Department of Food and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of São Paulo 05508-000, Brazil.
Nutr Res. 2012 Jul;32(7):542-6. doi: 10.1016/j.nutres.2012.05.010. Epub 2012 Jun 22.
Deficiencies in calcium (Ca) and magnesium (Mg) are associated with various complications during pregnancy. To test the hypothesis that the status of these minerals is inadequate in pregnancy, a cross-sectional study was conducted of the dietary intake and status of Ca and Mg in pregnant women (n = 50) attending a general public university hospital in Brazil. Dietary intake was assessed from 4-day food records; levels of plasma Mg, erythrocyte Mg, and urinary Ca and Mg excretion were determined by flame atomic absorption spectroscopy; and type I collagen C-telopeptides were evaluated by enzyme-linked immunosorbent assay. Probabilities of inadequate Ca and Mg intake were exhibited by 58 and 98% of the study population, respectively. The mean levels of urinary Ca and Mg excretion were 8.55 and 3.77 mmol/L, respectively. Plasma C-telopeptides, plasma Mg, and erythrocyte Mg were within normal levels. Multiple linear regression analysis revealed positive relationships among urinary Ca excretion, Ca intake (P = .002) and urinary Mg excretion (P < .001) and between erythrocyte Mg and Mg intake (P = .023). It is concluded that the Ca and Mg status of participants was adequate even though the intake of Ca and Mg was lower than the recommended level.
钙（Ca）和镁（Mg）缺乏与妊娠期间的各种并发症有关。为了验证矿物质状态在妊娠期间不足的假设，对巴西一所公立大学附属医院的 50 名孕妇进行了横断面研究，以检测她们的膳食摄入和 Ca 和 Mg 状态。通过 4 天的食物记录评估膳食摄入；通过火焰原子吸收光谱法测定血浆 Mg、红细胞 Mg 以及尿 Ca 和 Mg 排泄水平；通过酶联免疫吸附试验评估 I 型胶原 C 端肽。分别有 58%和 98%的研究人群显示 Ca 和 Mg 摄入不足的可能性。尿 Ca 和 Mg 排泄的平均水平分别为 8.55 和 3.77mmol/L。血浆 C 端肽、血浆 Mg 和红细胞 Mg 均处于正常水平。多元线性回归分析显示，尿 Ca 排泄与 Ca 摄入呈正相关（P=0.002）和尿 Mg 排泄（P<0.001）之间，以及红细胞 Mg 与 Mg 摄入之间呈正相关（P=0.023）。结论是，尽管 Ca 和 Mg 的摄入量低于推荐水平，但参与者的 Ca 和 Mg 状态是充足的。
