Mashour George A, Pal Dinesh
Department of Anesthesiology, University of Michigan Medical School, 1H247 University Hospital, Ann Arbor, MI 48109, USA.
Anesthesiol Clin. 2012 Jun;30(2):385-98. doi: 10.1016/j.anclin.2012.05.003. Epub 2012 Jun 23.
In the past decades there has been an increasing focus on the relationship of sleep and anesthesia. This relationship bears on the fundamental scientific questions in anesthesiology, such as the mechanism of anesthetic-induced unconsciousness. However, given the increasing prevalence of sleep disorders in surgical patients, the interfaces of sleep and anesthesia are now a pressing clinical concern. This article discusses sleep and anesthesia from the perspective of phenotype, mechanism and function, with some concluding thoughts on the relevance to neuroanesthesiology.
在过去几十年里，人们越来越关注睡眠与麻醉的关系。这种关系涉及麻醉学中的一些基本科学问题，比如麻醉诱导意识消失的机制。然而，鉴于外科手术患者睡眠障碍的患病率不断上升，睡眠与麻醉的交叉领域如今已成为一个紧迫的临床问题。本文从表型、机制和功能的角度探讨睡眠与麻醉，并对其与神经麻醉学的相关性给出一些总结性思考。
