定义子宫收缩过频：多少算过多？
Defining uterine tachysystole: how much is too much?
机构信息
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9032, USA.
出版信息
Am J Obstet Gynecol. 2012 Oct;207(4):290.e1-6. doi: 10.1016/j.ajog.2012.07.032. Epub 2012 Jul 31.
OBJECTIVE
We sought to determine if uterine tachysystole, ≥ 6 contractions per 10 minutes, within the first 4 hours of labor induction, is associated with adverse infant outcomes.
STUDY DESIGN
This was a prospective cohort study of 584 women ≥ 37 weeks' gestation undergoing induction of labor with 100 μg of oral misoprostol. Fetal heart rate tracings were analyzed for contractions per 10 minutes during the initial 4 hours after misoprostol administration. Patients were analyzed based on the maximum number of contractions per 10 minutes. Infant condition at birth was assessed using the fetal vulnerability composite.
RESULTS
Adverse infant outcomes showed no association with increasing number of contractions per 10 minutes. Six or more contractions in 10 minutes were significantly associated with fetal heart rate decelerations (P ≤ .001). Analysis was performed using the maximum number of contractions per 30 minutes with similar results.
CONCLUSION
Uterine tachysystole, as currently defined, when occurring remote from delivery is not associated with adverse infant outcomes.
目的
我们旨在确定分娩诱导后 4 小时内每 10 分钟≥6 次的子宫收缩是否与婴儿不良结局相关。
研究设计
这是一项对 584 名≥37 周妊娠且接受 100μg 口服米索前列醇引产的妇女进行的前瞻性队列研究。在米索前列醇给药后的最初 4 小时内，分析胎儿心率监测图中每 10 分钟的宫缩次数。根据每 10 分钟的最大宫缩数对患者进行分析。使用胎儿易损性综合指标评估出生时婴儿的状况。
结果
不良婴儿结局与每 10 分钟宫缩次数的增加无关联。每 10 分钟 6 次或更多的宫缩与胎心减速显著相关（P≤0.001）。使用每 30 分钟最大宫缩数进行分析得到了类似的结果。
结论
目前定义的分娩诱导后 4 小时内的子宫收缩过速，与不良婴儿结局无关。
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