Department of Radiology, Taipei City Hospital, Taipei, Taiwan, ROC.
J Chin Med Assoc. 2012 Aug;75(8):384-8. doi: 10.1016/j.jcma.2012.06.002. Epub 2012 Jul 21.
Magnetic resonance cholangiopancreatography (MRCP) is a popular modality for evaluation of the biliary tract, yet there is no data on the normal common bile duct (CBD) size of the average Taiwanese adult. This study attempts to establish a reference range for CBD diameter for the Taiwanese population.
Over a 2-year period, all adults who underwent abdominal magnetic resonance imaging for health screening were recruited into the study. Patients with a prior history of hepatobiliary surgery and other significant morbidity were not included. Patients who were found to have abnormal liver function test results or abnormal imaging findings were also excluded from the study. After the patients fasted for a minimum of 8 hours, MR imaging was performed with a 1.5 T MR imager using a phased-array coil. Breath-hold thick slab single-shot turbo spin echo (ssTSE BH) projections were obtained, and these were used for CBD and portal vein diameter (PVD) measurement by workstation software. Initial recruitment included 265 patients, of which 66 were excluded due to abnormal liver function tests, seven more were excluded due to excess imaging artifacts or incomplete CBD visualization, and five were excluded due to other abnormal blood tests. This yielded a final study group of 187 patients between the ages of 21 and 78 years, which comprised 69 women and 118 men.
The mean CBD diameter is 4.6 mm, with a range from 1.76 to 10.49 mm. CBD diameters are significantly different in patients both younger and older than 65 years of age (p < 0.05), and are not significantly related to gender, serum glucose level, cholesterol level, hepatitis status and PVD.
Our study showed that the average CBD diameter for an asymptomatic Taiwanese adult is 4.6 mm, with an upper limit of 10.49 mm. CBD diameter is only significantly correlated with age. This is a useful reference in today's clinical setting where MRCP are commonly performed for evaluation of suspected biliary tract disease.
磁共振胰胆管成像（MRCP）是评估胆道的常用方法，但目前尚无关于台湾成年人正常胆总管（CBD）大小的相关数据。本研究旨在建立台湾人群 CBD 直径的参考范围。
在两年的时间里，所有因健康筛查而接受腹部磁共振成像的成年人都被纳入研究。既往有肝胆手术史和其他严重合并症的患者不纳入本研究。同时，排除有异常肝功能检查结果或异常影像学表现的患者。患者禁食至少 8 小时后，使用 1.5 T 磁共振成像仪和相控阵线圈进行 MR 成像。采集屏气厚片单次激发快速自旋回波（ssTSE BH）投影，工作站软件用于测量 CBD 和门静脉直径（PVD）。初步招募了 265 名患者，其中 66 名因肝功能检查异常被排除，7 名因过多的影像学伪影或不完全的 CBD 可视化被排除，5 名因其他异常血液检查被排除。最终研究组纳入了 187 名年龄在 21 至 78 岁之间的患者，其中包括 69 名女性和 118 名男性。
CBD 直径的平均值为 4.6 毫米，范围为 1.76 至 10.49 毫米。年龄小于 65 岁和大于 65 岁的患者 CBD 直径有显著差异（p < 0.05），且与性别、血糖水平、胆固醇水平、肝炎状态和 PVD 均无显著相关性。
我们的研究表明，无症状台湾成年人群的平均 CBD 直径为 4.6 毫米，上限为 10.49 毫米。CBD 直径仅与年龄显著相关。这在当今临床环境中具有重要意义，MRCP 常用于评估疑似胆道疾病。
