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脆弱拟杆菌,常被误鉴定为“梭状芽胞杆菌梭菌组”,与罕见的人类感染病例有关。

Clostridium celerecrescens, often misidentified as "Clostridium clostridioforme group," is involved in rare human infection cases.

机构信息

Institut Pasteur, Centre National de Référence des Bactéries Anaérobies et du Botulisme, Unité Bactéries anaérobies et Toxines, 25-28 rue du Docteur Roux, F-75724 Paris cedex 15, France.

出版信息

Diagn Microbiol Infect Dis. 2012 Nov;74(3):299-302. doi: 10.1016/j.diagmicrobio.2012.06.024. Epub 2012 Aug 15.

DOI:10.1016/j.diagmicrobio.2012.06.024
PMID:22901791
Abstract

Misidentification of rare Clostridium species often originated from the environment as clinically relevant species is problematic. A strain isolated from a traumatic leg wound first identified as C. clostridioforme was finally identified as the rare Clostridium celerecrescens. Two similar misidentifications are reported in the literature. In order to help the phenotypic differentiation of C. celerecrescens from the close species of the "C. clostridioforme group", an identification table and differential susceptibilities to 4 selected antibiotics are proposed. Once a clinical isolate is referred to this group, identification should be definitively confirmed by unambiguous methods such as 16s rDNA sequencing.

摘要

罕见梭菌种类的错误鉴定通常源于环境,因为将临床相关的种类鉴定为罕见梭菌是有问题的。从创伤性腿部伤口中分离出的一株菌最初被鉴定为 C. clostridioforme,最终被鉴定为罕见的 C. celerecrescens。文献中报道了两起类似的错误鉴定。为了帮助从“C. clostridioforme 组”的密切相关物种中区分 C. celerecrescens,提出了一个鉴定表和对 4 种选定抗生素的差异敏感性。一旦临床分离株被归入该组,应通过 16s rDNA 测序等明确方法来明确确认鉴定。

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