Institute for Cardiovascular and Metabolic Medicine, Mariatrosterstr. 67, A8043 Graz, Austria.
Med Eng Phys. 2013 May;35(5):616-25. doi: 10.1016/j.medengphy.2012.07.006. Epub 2012 Aug 14.
Aim of the study was to assess the accuracy and precision of a BIS device and the relative contribution of BIS beyond the anthropometric parameters. The output of the Impedimed device (SFB7) and the relative contribution of height, weight, age, sex and resistance values at zero and infinite frequency (Rzero and Rinf respectively) to the prediction of total body water (TBWd, deuterium space), of extracellular fluid (ECFbr, sodium bromide space) and of fat mass (FMDXA) were assessed in 116 subjects (32 healthy subjects and 84 patients with disorders of body composition). Using a repeated randomization procedure, new equations for TBW, ECF and FM were derived. The SFB7 gave measures of determination similar to those obtained with equations that included only anthropometric data. The SFB7, but not the newly derived regression equations, underestimated TBW and ECF by 3.82±3.37 (mean±SD) and by 0.93±2.62l and overestimated FM by 6.55±3.86kg. Nine of 16 patients with ECF overload as detected by ECFbr were also detected by BIS. BIS measurements contribute marginally but not significantly beyond anthropometric data to the prediction of TBW, ECF and FM, either in healthy subjects or in patients with disturbed body composition.
目的是评估 BIS 设备的准确性和精密度，以及 BIS 除人体测量参数外的相对贡献。在 116 名受试者（32 名健康受试者和 84 名体成分紊乱患者）中评估了 Impedimed 设备（SFB7）的输出以及身高、体重、年龄、性别和零频和无穷频电阻值（Rzero 和 Rinf 分别）对总体水（TBWd，氘空间）、细胞外液（ECFbr，溴化钠空间）和脂肪量（FMDXA）的预测的准确性和精密度。使用重复随机化程序，推导出了新的 TBW、ECF 和 FM 方程。SFB7 给出的决定系数与仅包含人体测量数据的方程相当。SFB7 不仅低估了 TBW 和 ECF，分别低估了 3.82±3.37（均值±SD）和 0.93±2.62l，而且高估了 FM，高估了 6.55±3.86kg。在通过 ECFbr 检测到 ECF 过载的 16 名患者中，有 9 名也通过 BIS 检测到。BIS 测量值除了人体测量数据外，对 TBW、ECF 和 FM 的预测仅有微小但无统计学意义的贡献，无论是在健康受试者还是体成分紊乱患者中。
