Inoue H
1st Dept. Int. Med., Tohoku Univ. Sch. Med., Sendai, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1990 Nov;28(11):1395-7.
To determine aerosol size distribution of several particle generators for the inhalation therapy we employed a laser scattering method and QCM cascade impactor method. The particle size distribution measured by the latter method showed MDI less than Diskhaler less than Jet nebulizer, the smaller in order. Our model analysis also suggests that an usage of a spacer (especially the size of around 150 ml) enable to increase the total amount of aerosol inhalation into the lungs, when MDI is applied as an aerosol generator.
为了确定用于吸入疗法的几种颗粒发生器的气溶胶粒径分布,我们采用了激光散射法和QCM级联撞击器法。通过后一种方法测量的粒径分布显示,定量吸入器(MDI)产生的粒径小于都保(Diskhaler)产生的粒径,都保产生的粒径又小于喷射雾化器产生的粒径,依次变小。我们的模型分析还表明,当使用定量吸入器作为气溶胶发生器时,使用储雾罐(尤其是容量约为150毫升的)能够增加肺部吸入的气溶胶总量。