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自评健康:预测 2 型糖尿病患者三年内发生重度抑郁症的指标。

Self-rated health: a predictor for the three year incidence of major depression in individuals with Type II diabetes.

机构信息

Department of Psychiatry, McGill University, Montreal, Quebec, Canada.

出版信息

J Affect Disord. 2013 Feb 15;145(1):100-5. doi: 10.1016/j.jad.2012.07.018. Epub 2012 Aug 14.

DOI:10.1016/j.jad.2012.07.018
PMID:22902269
Abstract

BACKGROUND

To determine whether self-rated health was a predictor for the three year incidence of major depression in people with Type II diabetes.

METHODS

Data was collected as part a population-based telephone survey of adults with diabetes, in Québec, Canada (2008-2011). Adults with Type II diabetes who did not have major depression at baseline were assessed at three follow-up interviews conducted 12, 24 and 36 months after baseline. Depression was assessed using the Patient Health Questionnaire (PHQ-9). Self-rated health status was determined by asking participants to rate their health on a scale from excellent to poor.

RESULTS

The sample consisted of 1265 adults with Type II diabetes who did not have major depression at baseline. 36% of individuals who had developed major depression at follow up rated their health as fair or poor at baseline compared to 14.4% of those who had not developed major depression. Logistic regression analyses indicated fair or poor self-rated health at baseline to be predictive of a twofold increased risk for major depression at follow-up, even after adjusting for socio-demographic characteristics, lifestyle-related behaviors, disability and diabetes characteristics (OR=2.05, 95% CI 1.20-3.48).

LIMITATIONS

We have focused on current depression (last two weeks) and we have used a questionnaire (PHQ-9) rather than a clinical interview for the assessment of depression.

CONCLUSIONS

Self-rated health status might be a predictor for developing major depression in people with diabetes in addition to well established risk factors.

摘要

背景

本研究旨在探讨自评健康状况是否可预测 2 型糖尿病患者三年内发生重度抑郁症的风险。

方法

该研究数据来自于加拿大魁北克省一项基于人群的成年人糖尿病电话调查(2008-2011 年)。基线时无重度抑郁症的 2 型糖尿病患者在基线后 12、24 和 36 个月分别进行了 3 次随访访谈。采用患者健康问卷(PHQ-9)评估抑郁状况。自评健康状况通过询问参与者对自己的健康状况进行评分(从优秀到差)来确定。

结果

本研究共纳入 1265 例基线时无重度抑郁症的 2 型糖尿病患者。与未发生重度抑郁症的患者相比,在随访中发生重度抑郁症的患者中有 36%在基线时自评健康状况为一般或差,而未发生重度抑郁症的患者中仅有 14.4%自评健康状况为一般或差。Logistic 回归分析表明,基线时自评健康状况一般或差与随访时发生重度抑郁症的风险增加两倍相关,即使在校正了社会人口学特征、生活方式相关行为、残疾和糖尿病特征后(OR=2.05,95%CI 1.20-3.48)。

局限性

我们关注的是当前的抑郁(过去两周),并且我们使用问卷(PHQ-9)而不是临床访谈来评估抑郁。

结论

自评健康状况可能是除已确定的危险因素之外,预测糖尿病患者发生重度抑郁症的一个指标。

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