Kachalkov D V, Pomerantsev E V, Gratsianskiĭ N A, Savchenko A P
Kardiologiia. 1990 Oct;30(10):20-3.
Thirty patients with first angina (FA) underwent repeated coronary angiographic examinations in the first 3 months of the disease and 15.0 +/- 3.1 (M +/- sigma) after. At the second coronary angiography, 9 (30%) patients developed a clinical remission. The time course of stenoses was assessed by a quantitative method such as the vessel contour outline one. Six (20%) patients displayed stenosis regression, 5 (17%) had both regression and progression, 11 (37%) exhibited progression, 8 (26%) showed no changes. The multifactorial discriminant step-by-step analysis was employed to assess the predictive value of various clinical, bicycle ergometric, lipid, and angiographic factors in the time course of stenoses. In the first year of the follow-up, stenosis regression was seen in 20% of the FA patients. By the second coronary angiography, the patients with remained angina showed a high probability that there had been a progression of at least one stenosis. The probability was also high in patients with less obesity, a greater number of affected vessels and a more severity of the disease in the first month.
30例初发型心绞痛（FA）患者在发病后的前3个月及之后15.0±3.1（均数±标准差）个月接受了多次冠状动脉造影检查。在第二次冠状动脉造影时，9例（30%）患者出现临床缓解。通过定量方法（如血管轮廓法）评估狭窄的时间进程。6例（20%）患者出现狭窄消退，5例（17%）既有消退又有进展，11例（37%）表现为进展，8例（26%）无变化。采用多因素判别逐步分析来评估各种临床、自行车运动负荷试验、血脂和血管造影因素对狭窄时间进程的预测价值。在随访的第一年，20%的FA患者出现狭窄消退。到第二次冠状动脉造影时，仍有心绞痛的患者至少有一处狭窄进展的可能性很高。在第一个月肥胖程度较轻、受累血管数量较多且病情较重的患者中，这种可能性也很高。
