Akos Pákozdy, Thalhammer Johann G, Leschnik Michael, Halász Péter
University of Veterinary Medicine Clinic for Internal Medicine for Small Animals A-1210 Veterinärplatz 1 Vienna Austria.
Acta Vet Hung. 2012 Sep;60(3):309-24. doi: 10.1556/AVet.2012.026.
The main aim of this study was to identify interictal epileptiform discharges in a group of dogs with seizures of known aetiology (symptomatic epilepsy, SE) and in dogs with idiopathic epilepsy (IE). Propofol was used for chemical restraint in all dogs. We found electroencephalographic (EEG) changes that could be considered epileptiform discharges (EDs) in 5 out of 40 dogs (12.5%). The EEG changes identified were spikes in four cases and periodic epileptiform discharges in one case. All EDs were seen in the SE group. We conclude that the interictal electroencephalographic examinations of propofolanaesthetised dogs suffering from IE and SE rarely show epileptic discharges and that the diagnostic value of such EEGs in the work-up for epilepsy seems to be low as epileptic discharges were unlikely to be detected. However, positive findings are more likely to be connected with SE. We found frequent, transient EEG phenomena (spindles, K-complexes, vertex waves, positive occipital sharp transients of sleep, cyclic alternating patterns), which are non-epileptic but their differentiation from epileptic phenomena is challenging.
本研究的主要目的是在一组病因已知的癫痫发作犬（症状性癫痫，SE）和特发性癫痫（IE）犬中识别发作间期癫痫样放电。所有犬均使用丙泊酚进行化学保定。我们在40只犬中的5只（12.5%）发现了可被视为癫痫样放电（EDs）的脑电图（EEG）变化。所识别出的EEG变化在4例中为棘波，1例为周期性癫痫样放电。所有EDs均出现在SE组中。我们得出结论，患有IE和SE的丙泊酚麻醉犬的发作间期脑电图检查很少显示癫痫放电，并且由于不太可能检测到癫痫放电，此类脑电图在癫痫检查中的诊断价值似乎较低。然而，阳性结果更可能与SE相关。我们发现了频繁的、短暂的EEG现象（纺锤波、K复合波、顶波、睡眠时枕部正相尖波、周期性交替模式），这些现象是非癫痫性的，但将它们与癫痫现象区分开来具有挑战性。
