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[脑循环障碍患者的微循环状态及血液流变学特性]

[Status of microcirculation and rheological properties of blood in patients with cerebral circulatory disorders].

作者信息

Lebedeva N V, Lobkova T N, Ionova V G, Khrapova E V

出版信息

Klin Med (Mosk). 1990 Sep;68(9):31-3.

PMID:2290322
Abstract

Microcirculation and rheological properties of blood were investigated over time on the basis of the findings of biomicroscopy of the bulbar conjunctiva in 61 patients with different stages of circulatory encephalopathy in the presence of arterial hypertension and atherosclerosis. Rheological properties of blood were changed at all stages of disease. Correlations between the ability of erythrocytes to aggregation and the degree of their intravascular aggregation by the findings of biomicroscopy of the bulbar conjunctiva were not found. The importance of investigation of the intravascular aggregation of erythrocytes and theological properties of blood for assessment of the cerebral vascular microcirculation, control of therapy, and verification of some aspects of the mechanism of action of various drugs was shown.

摘要

基于对61例患有不同阶段循环性脑病且伴有动脉高血压和动脉粥样硬化患者的球结膜生物显微镜检查结果,对血液的微循环和流变学特性进行了长期研究。在疾病的各个阶段,血液的流变学特性均发生了变化。通过球结膜生物显微镜检查结果,未发现红细胞聚集能力与其血管内聚集程度之间的相关性。研究表明,红细胞血管内聚集及血液流变学特性的研究对于评估脑血管微循环、控制治疗以及验证各种药物作用机制的某些方面具有重要意义。

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