[Characteristics of various indicators of the rheological properties of the blood in patients with initial manifestations of cerebrovascular insufficiency and ischemic stroke].

The rheological properties of the blood and aggregation of erythrocytes and platelets were studied in 30 apparently healthy subjects and in 220 patients with impaired blood supply to the brain. The results have confirmed a high informative value of the complex of parameters of rotational viscosimetry: the limit of blood fluidity, apparent blood viscosity, caisson viscosity of the blood, and the coefficient of erythrocyte cohesion (A) and of the parameters of aggregation of the formed elements of the blood, this complex allowing an objective differentiation between microcirculatory peculiarities in patients with initial manifestations of cerebral blood supply insufficiency (IMCBSI) versus patients with ischemic stroke (IS). It has been elucidated for the first time that patients with IMCBSI secondary to atherosclerosis have a low A parameter confirming optimization of the microcirculation following elevation of the hematocrit. The alterations in the rheological properties of the blood were the greatest in patients with IS within the first three days after the onset of the disease. Elevated cohesion of erythrocytes persisted for one month after the onset of IS. It has been proved that repeated examinations are necessary for the individual and adequate correction of the blood rheology.