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本文引用的文献

1
Genetic susceptibility in pituitary adenomas: from pathogenesis to clinical implications.垂体腺瘤的遗传易感性:从发病机制到临床意义
Expert Rev Endocrinol Metab. 2011 Mar;6(2):195-214. doi: 10.1586/eem.10.87.
2
No evidence of a detrimental effect of cabergoline therapy on cardiac valves in patients with acromegaly.没有证据表明卡麦角林治疗肢端肥大症会对心脏瓣膜造成损害。
J Clin Endocrinol Metab. 2012 Sep;97(9):E1714-9. doi: 10.1210/jc.2012-1833. Epub 2012 Jun 21.
3
Clinical implications of growth hormone-secreting tumor subtypes.生长激素分泌肿瘤亚型的临床意义。
Endocrine. 2012 Aug;42(1):18-28. doi: 10.1007/s12020-012-9660-9. Epub 2012 Mar 21.
4
Determinants of cardiac disease in newly diagnosed patients with acromegaly: results of a 10 year survey study.新诊断的肢端肥大症患者心脏病的决定因素:一项 10 年调查研究的结果。
Eur J Endocrinol. 2011 Nov;165(5):713-21. doi: 10.1530/EJE-11-0408. Epub 2011 Aug 25.
5
Pregnancy in acromegaly: experience from two referral centers and systematic review of the literature.肢端肥大症患者的妊娠:来自两个转诊中心的经验和文献系统综述。
Clin Endocrinol (Oxf). 2012 Feb;76(2):264-71. doi: 10.1111/j.1365-2265.2011.04180.x.
6
Improvement of cardiac parameters in patients with acromegaly treated with medical therapies.医学治疗改善肢端肥大症患者的心脏参数。
Pituitary. 2012 Mar;15(1):50-8. doi: 10.1007/s11102-011-0318-z.
7
Influence of diabetes mellitus on vertebral fractures in men with acromegaly.糖尿病对肢端肥大症男性患者椎体骨折的影响。
Endocrine. 2011 Aug;40(1):102-8. doi: 10.1007/s12020-011-9486-x. Epub 2011 May 19.
8
High prevalence of vertebral fractures despite normal bone mineral density in patients with long-term controlled acromegaly.长期控制良好的肢端肥大症患者,尽管骨密度正常,但仍存在高发的椎体骨折。
Eur J Endocrinol. 2011 Apr;164(4):475-83. doi: 10.1530/EJE-10-1005. Epub 2011 Jan 21.
9
Effects of high-dose octreotide LAR on glucose metabolism in patients with acromegaly inadequately controlled by conventional somatostatin analog therapy.奥曲肽长效释放剂(LAR)大剂量治疗对常规生长抑素类似物治疗控制不佳的肢端肥大症患者糖代谢的影响。
Eur J Endocrinol. 2011 Mar;164(3):341-7. doi: 10.1530/EJE-10-0811. Epub 2011 Jan 6.
10
Arthropathy in long-term cured acromegaly is characterised by osteophytes without joint space narrowing: a comparison with generalised osteoarthritis.肢端肥大症长期治愈后的关节病的特征是骨赘形成而无关节间隙变窄:与全身性骨关节炎的比较。
Ann Rheum Dis. 2011 Feb;70(2):320-5. doi: 10.1136/ard.2010.131698. Epub 2010 Dec 3.

关于肢端肥大症并发症的诊断和治疗的共识。

A consensus on the diagnosis and treatment of acromegaly complications.

机构信息

Department of Medicine, Cedars-Sinai Medical Center, 8700 Beverly Blvd., Room 2015, Los Angeles, CA 90048, USA.

出版信息

Pituitary. 2013 Sep;16(3):294-302. doi: 10.1007/s11102-012-0420-x.

DOI:10.1007/s11102-012-0420-x
PMID:22903574
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3730092/
Abstract

In March 2011, the Acromegaly Consensus Group met to revise and update the guidelines on the diagnosis and treatment of acromegaly complications. The meeting was sponsored by the Pituitary Society and the European Neuroendocrinology Association and included experts skilled in the management of acromegaly. Complications considered included cardiovascular, endocrine and metabolic, sleep apnea, bone diseases, and mortality. Outcomes in selected, related clinical conditions were also considered, and included pregnancy, familial acromegaly and invasive macroadenomas. The need for a new disease staging model was considered, and design of such a tool was proposed.

摘要

2011 年 3 月,肢端肥大症共识小组召开会议,修订和更新肢端肥大症并发症的诊断和治疗指南。会议由垂体学会和欧洲神经内分泌协会主办,邀请了肢端肥大症管理方面的专家参加。所考虑的并发症包括心血管、内分泌和代谢、睡眠呼吸暂停、骨疾病和死亡率。还考虑了选定的相关临床情况的结果,包括妊娠、家族性肢端肥大症和侵袭性大腺瘤。会议认为有必要建立新的疾病分期模型,并提出了此类工具的设计方案。