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[肢端肥大症伴睡眠呼吸暂停综合征]

[Acromegaly with the sleep apnea syndrome].

作者信息

Ferreira A M, César M H, Pissarra C, dos Santos F J, Moita J, Coelho I, Azevedo M H

机构信息

Serviço de Psiquiatria, Hospitais da Universidade de Coimbra.

出版信息

Acta Med Port. 1997 Dec;10(12):955-9.

PMID:9522495
Abstract

The authors present the clinical of a male patient aged 45 years whose main complaints were loud snoring and excessive daytime sleepiness. Polysomnographic study revealed a sleep obstructive apnea syndrome with an apnea/hypopnea index of 86.5. After being treated with nasal continuous positive air pressure, (12 cm H2O), the apneas ended and sleep architecture was corrected. Physical examination also indicated the presence of an acromegaly, and therefore, the patient was subjected to endocrinological and cerebral imagiological studies; the diagnosis confirmed it as a predisposing factor to the sleep breathing disorder. A brief literature review about the incidence of sleep apnea syndrome in acromegaly is also made; the authors conclude that there is still the need for a systematic screening of sleep breathing disorders in acromegalic patients in order to optimise the treatment and prognosis of this disorders.

摘要

作者介绍了一名45岁男性患者的临床情况,其主要症状为大声打鼾和日间过度嗜睡。多导睡眠图研究显示为睡眠呼吸暂停综合征,呼吸暂停/低通气指数为86.5。经鼻持续气道正压通气(12厘米水柱)治疗后,呼吸暂停终止,睡眠结构得到纠正。体格检查还表明存在肢端肥大症,因此,该患者接受了内分泌学和脑影像学检查;诊断证实这是睡眠呼吸障碍的一个诱发因素。作者还对肢端肥大症中睡眠呼吸暂停综合征的发病率进行了简要文献综述;作者得出结论,仍有必要对肢端肥大症患者进行睡眠呼吸障碍的系统筛查,以优化该疾病的治疗和预后。

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