Pannenbecker J, Miller T C, Müller J, Jeschke R
Kinderklinik und Kinderpoliklinik, Universität Würzburg.
Monatsschr Kinderheilkd. 1990 Nov;138(11):767-71.
Human hepatic capillariasis is a rare disease, which predominantly affects children aged 1 to 4 years and has a poor prognosis in extensive infections. This is the first case observed in Germany. The main symptoms are those of severe parasitosis: persistent high fever, hepatomegaly, and excessive hypereosinophilia. Diagnosis is confirmed by the finding of intracellular typical eggs in liver biopsy. There is a lack of established therapy; our 18 months old girl developed liver fibrosis. She survived under a prolonged treatment with high doses of Thiabendazole and two single doses of Ivermectine. Decortin was given to inhibit further granulomatous processes in the liver.
人类肝毛细线虫病是一种罕见疾病，主要影响1至4岁儿童，广泛感染时预后较差。这是在德国观察到的首例病例。主要症状为严重寄生虫病的症状：持续高烧、肝肿大和极度嗜酸性粒细胞增多。通过肝活检发现细胞内典型虫卵来确诊。目前缺乏既定的治疗方法；我们18个月大的女童出现了肝纤维化。她在大剂量噻苯达唑长期治疗和两剂单剂量伊维菌素的治疗下存活下来。给予了地塞米松以抑制肝脏进一步的肉芽肿形成过程。
