Choe G, Lee H S, Seo J K, Chai J Y, Lee S H, Eom K S, Chi J G
Department of Pathology, Seoul National University College of Medicine, Republic of Korea.
Am J Trop Med Hyg. 1993 May;48(5):610-25. doi: 10.4269/ajtmh.1993.48.610.
We report a case of massive hepatic infection by Capillaria hepatica in a 14-month-old girl who presented with the symptom triad of persistent fever, hepatomegaly, and leukocytosis with eosinophilia. Twenty-five cases of human infection with this parasite, mostly in children, have been reported in the literature. This is the first case of hepatic capillariasis reported in the Republic of Korea. The diagnosis was made by needle biopsy of the liver. Scanning electron microscopic examination of the biopsy specimen was also performed. Thiabendazole therapy was initiated and the patient developed liver disease-related IgA nephropathy during the therapy. The literature dealing with proven cases of infection with C. hepatica is briefly reviewed.
我们报告了一例14个月大女童发生肝毛细线虫大量肝内感染的病例,该女童出现持续发热、肝肿大以及伴有嗜酸性粒细胞增多的白细胞增多三联征症状。文献中已报道了25例人类感染这种寄生虫的病例,其中大多数为儿童。这是韩国报道的首例肝毛细线虫病病例。通过肝脏穿刺活检做出诊断。还对活检标本进行了扫描电子显微镜检查。开始使用噻苯达唑治疗,治疗期间患者出现了与肝脏疾病相关的IgA肾病。本文简要回顾了已证实的肝毛细线虫感染病例的相关文献。