Omundsen Mark, Lam Francis F
Department of Colorectal Surgery, Prince of Wales Hospital, Sydney, New South Wales, Australia.
ANZ J Surg. 2012 Oct;82(10):675-81. doi: 10.1111/j.1445-2197.2012.06140.x. Epub 2012 Aug 21.
Familial colorectal cancer syndromes have been increasingly recognized and through their characterization have contributed to our understanding of the genetic basis of colorectal cancer. The two main syndromes of familial adenomatous polyposis and hereditary non-polyposis coli are the commonest. There is however a number of lesser known syndromes described, which is the focus of this article.
家族性结直肠癌综合征已越来越多地被认识到,通过对它们的特征描述,有助于我们理解结直肠癌的遗传基础。家族性腺瘤性息肉病和遗传性非息肉病性结直肠癌这两种主要综合征最为常见。然而,还有一些较少为人所知的综合征被描述,这正是本文的重点。