Zidichouski J A, Chen H, Smith P A
Department of Pharmacology, University of Alberta, Edmonton, Canada.
Neurosci Lett. 1990 Sep 4;117(1-2):123-8. doi: 10.1016/0304-3940(90)90130-2.
Neuropeptide Y (NPY) is found in the C-cells yet is absent from the B-cells of amphibian sympathetic ganglia. The effects of this peptide on both cell types were studied using the whole-cell patch-clamp recording technique. Although NPY had little effect on the B-cells, it opened inwardly-rectifying K(+)-channels in C-cells. This effect of the peptide on C-cell K(+)-channels was similar to that produced by muscarine and adrenaline and may be related to autoreceptor function.
神经肽Y（NPY）存在于两栖类交感神经节的C细胞中，但在B细胞中不存在。使用全细胞膜片钳记录技术研究了这种肽对两种细胞类型的影响。虽然NPY对B细胞几乎没有影响，但它能打开C细胞中的内向整流钾通道。该肽对C细胞钾通道的这种作用类似于毒蕈碱和肾上腺素所产生的作用，可能与自身受体功能有关。
