Department of Neurology, Keimyung University School of Medicine, Daegu, South Korea.
J Neurol Sci. 2012 Oct 15;321(1-2):17-22. doi: 10.1016/j.jns.2012.07.055. Epub 2012 Aug 17.
Acute vestibular syndrome (AVS) is characterized by acute onset of spontaneous prolonged vertigo (lasting days), spontaneous nystagmus, postural instability, and autonomic symptoms. Peripheral AVS commonly presents as vestibular neuritis, but may also include other disorders such as Meniere's disease. Vertigo in central AVS due to vertebrobasilar ischemic stroke is usually accompanied by other neurological dysfunction. However it can occur in isolation and mimicking peripheral AVS, particularly with cerebellar strokes. Recent large prospective studies have demonstrated that approximately 11% of patients with isolated cerebellar infarction presented with isolated vertigo mimicking peripheral AVS, and the bedside head impulse test is the most useful tool for differentiating central from peripheral AVS. Herein we review the keys to the diagnosis of central AVS of a vascular cause presenting with isolated vertigo or audiovestibular loss.
急性前庭综合征(AVS)的特点为急性起病、持续时间较长的自发性眩晕(持续数日)、自发性眼震、姿势不稳和自主神经症状。外周性 AVS 通常表现为前庭神经炎,但也可能包括梅尼埃病等其他疾病。由于椎基底动脉缺血性卒中引起的中枢性 AVS 性眩晕通常伴有其他神经功能障碍。然而,它也可以孤立出现并模拟外周性 AVS,特别是小脑卒中。最近的大型前瞻性研究表明,约 11%孤立性小脑梗死患者出现孤立性眩晕,模拟外周性 AVS,床边摇头试验是区分中枢性和外周性 AVS 的最有用工具。本文综述了血管性孤立性眩晕或听觉前庭损失的中枢性 AVS 的诊断要点。