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[体外肺支持]

[Extracorporeal lung support].

作者信息

Hecker M, Bandorski D, Hecker A

机构信息

Medizinische Klinik II (Pneumologie/internistische Intensivmedizin), Universitätsklinikum Gießen und Marburg, Standort Gießen, Klinikstraße 33, 35392, Gießen, Deutschland.

出版信息

Med Klin Intensivmed Notfmed. 2012 Sep;107(6):491-500; quiz 501. doi: 10.1007/s00063-012-0142-x. Epub 2012 Aug 22.

Abstract

For decades, techniques for extracorporeal lung support, such as extracorporeal membrane oxygenation (ECMO), have offered in specialized centres the possibility to completely or partly substitute lung function, thus, facilitating healing. Initially the application of ECMO was associated with severe complications, but significant technical progress in recent years has led to the development of safer systems and promotes a wider distribution of the technique. Supported by recent, positive study data, ECMO has become a promising option for acute respiratory distress syndrome (ARDS) therapy in specialized centers. Further developments and modifications, such as pumpless devices for extracorporeal lung support have the potential of becoming an interesting option for intensive care medicine - however, data of prospective studies showing efficacy are still not available.

摘要

几十年来,体外肺支持技术,如体外膜肺氧合(ECMO),已在专业中心提供了完全或部分替代肺功能的可能性,从而促进愈合。最初,ECMO的应用与严重并发症相关,但近年来显著的技术进步导致了更安全系统的开发,并促进了该技术更广泛的应用。在近期积极研究数据的支持下,ECMO已成为专业中心治疗急性呼吸窘迫综合征(ARDS)的一个有前景的选择。进一步的发展和改进,如用于体外肺支持的无泵设备,有可能成为重症医学的一个有趣选择——然而,显示疗效的前瞻性研究数据仍然不可用。

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