Dreyer T, Etschmann B, Kroll T, Bräuninger A, Gattenlöhner S, Benz A
Institut für Pathologie, Justus-Liebig-Universität Gießen, Langhansstr. 10, 35392, Gießen, Deutschland.
Pathologe. 2012 Sep;33(5):397-401. doi: 10.1007/s00292-012-1599-3.
The frozen section procedure for immediate intraoperative pathological diagnosis represents a pivotal method in tumor diagnosis. In laryngeal tumors the most frequent indication for the use of this method is the documentation of the residual tumor status, while intraoperative consultation with the purpose of primary tumor diagnosis is less common. The specimen management employed in each case should be chosen depending on the clinical question: while the collection of a maximum amount of tissue is advisable for the determination of the residual tumor status, sparing a portion of the remaining tissue for possible future examinations is advisable in the case of primary tumor diagnosis. Moreover, intraoperative frozen section diagnosis with no immediate consequences should be avoided.
用于术中即时病理诊断的冰冻切片程序是肿瘤诊断中的关键方法。在喉肿瘤中,使用该方法最常见的指征是记录残留肿瘤状态,而以原发性肿瘤诊断为目的的术中会诊则较少见。每种情况下采用的标本处理方式应根据临床问题来选择:对于确定残留肿瘤状态,建议采集最大量的组织;而在原发性肿瘤诊断的情况下,建议保留一部分剩余组织以备将来可能的检查。此外,应避免进行无即时后果的术中冰冻切片诊断。