Departament de Química Analítica i Química Orgànica, Universitat Rovira i Virgili, Tarragona, Spain.
J Sep Sci. 2012 Oct;35(19):2621-8. doi: 10.1002/jssc.201200451. Epub 2012 Aug 21.
Two novel high-specific surface area polymeric sorbents (HXLPP-SAXa and HXLPP-SAXb) were synthesised and evaluated as solid-phase extraction sorbents. The novel sorbents under study are based on hypercrosslinked polymer microspheres and designed specifically to offer ion-exchange properties; the specific polymers of interest in the current work have been chemically modified in such a way as to impart a tuneable level of strong anion-exchange character onto the sorbents. The novel sorbents were applied as strong anion-exchange sorbents in solid-phase extraction studies, with the goal being to selectively extract a group of acidic compounds from complex environmental samples in an efficient manner. Out of two HXLPP-SAX resins evaluated in this study, it was found that the sorbent with the lower ion-exchange capacity (HXLPP-SAXa) gave rise to the best overall performance characteristics and, indeed, was found to compare favourably to the solid-phase extraction performance of commercial strong anion-exchange sorbents. When the HXLPP-SAXa sorbent was applied to the solid-phase extraction of environmental water samples, the result showed quantitative and selective extraction of low levels of acidic pharmaceuticals from 500 mL of river water and 100 mL of effluent wastewater.
两种新型高比表面积聚合物吸附剂（HXLPP-SAXa 和 HXLPP-SAXb）被合成并评估为固相萃取吸附剂。研究中的新型吸附剂基于超交联聚合物微球，专门设计为提供离子交换特性；目前工作中感兴趣的特定聚合物经过化学修饰，赋予吸附剂可调的强阴离子交换特性水平。新型吸附剂作为强阴离子交换吸附剂应用于固相萃取研究，旨在从复杂环境样品中高效选择性地提取一组酸性化合物。在所研究的两种 HXLPP-SAX 树脂中，发现离子交换容量较低的吸附剂（HXLPP-SAXa）具有最佳的整体性能特征，实际上与商业强阴离子交换吸附剂的固相萃取性能相当。当 HXLPP-SAXa 吸附剂应用于环境水样的固相萃取时，结果表明可从 500mL 河水和 100mL 废水样中定量和选择性地提取低浓度的酸性药物。
