Hustin J, Jauniaux E, Schaaps J P
Institut de Morphologie Pathologique, Loverval, Belgium.
Placenta. 1990 Nov-Dec;11(6):477-86. doi: 10.1016/s0143-4004(05)80193-6.
In a histological study of 184 specimens of complete spontaneous abortion, the following points were delineated. In cases of anomaly or death of the conceptus, there was a reduced trophoblastic penetration into the decidua and into the spiral arteries where physiological changes were limited or absent. Trophoblastic proliferation within the columns and the outer shell was limited with frequent disruption or even disappearance of the shell. These findings seem to be related to the untimely initiation of blood flow in the intervillous space which in turn is associated with arrest of pregnancy and eventual expulsion.
在一项对184例完全自然流产标本的组织学研究中，明确了以下几点。在胚胎异常或死亡的病例中，滋养层细胞向蜕膜和螺旋动脉的浸润减少，而这些部位的生理变化有限或不存在。柱状结构和外层中的滋养层细胞增殖受限，外层常有破坏甚至消失。这些发现似乎与绒毛间隙血流的过早启动有关，而这又与妊娠停滞及最终排出有关。
