Teodoro W R, Andreucci D, Palma J A
Department of Medicine, School of Medicine, University of São Paulo, Brazil.
Placenta. 1990 Nov-Dec;11(6):549-51. doi: 10.1016/s0143-4004(05)80200-0.
Collagen content of 43 placentae from clinically normal females who went into labour spontaneously was determined by assaying hydroxyproline. In 23 cases the membranes ruptured before or at the beginning of labour, and in 20 cases the rupture was intrumentally provoked during the expulsive period. In the group with prematurely ruptured membranes, hydroxyproline concentration was 11.52 +/- 1.83 micrograms/mg lyophilized tissue, whereas in the other group concentration was 20.29 +/- 4.32 micrograms/mg tissue. These data disclose a much lower collagen placental content in the group with premature rupturing of the membranes.
通过检测羟脯氨酸来测定43例自然分娩的临床正常女性胎盘的胶原蛋白含量。其中23例胎膜在临产前或临产开始时破裂，20例胎膜破裂是在娩出期人工诱发的。胎膜早破组的羟脯氨酸浓度为11.52±1.83微克/毫克冻干组织，而另一组的浓度为20.29±4.32微克/毫克组织。这些数据表明，胎膜早破组胎盘胶原蛋白含量低得多。
