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青少年免疫召回干预的随机对照试验。

Randomized controlled trial of an immunization recall intervention for adolescents.

机构信息

Division of Adolescent/Young Adult Medicine, Department of Medicine, Boston Children’s Hospital, Boston, Massachusetts, USA.

出版信息

Pediatrics. 2012 Sep;130(3):507-14. doi: 10.1542/peds.2012-0471. Epub 2012 Aug 20.

DOI:10.1542/peds.2012-0471
PMID:22908112
Abstract

OBJECTIVE

Determine if adolescent immunization rates can be improved by contacting the parents or by contacting both the parents and adolescents.

METHODS

Thirteen- to 17-year-olds overdue for at least 1 of 3 immunizations were randomized to (1) a control arm (Control), (2) telephone calls to the parent/guardian (Parent Only), or (3) telephone calls to the parent/guardian and the adolescent (Parent/Adol). Immunization records were assessed 4 weeks and 1 year after the intervention. Two-sided χ(2) tests and logistic regression models were used to compare receipt of immunizations by study arm.

RESULTS

The intention-to-treat analysis showed improved immunization rates at 4 weeks (adjusted odds ratio 2.27, 95% confidence interval 1.00-5.18), but not at 1 year, in the Parent/Adol group compared with controls. There was a trend toward increased immunization in the Parent Only group (odds ratio 2.02, 95% confidence interval 0.89-4.56). However, phone contact was not achieved for many parents and adolescents in the intervention groups. A post hoc analysis of the impact of actual phone contact showed significant improvement in immunization rates both 4 weeks and 1 year after the intervention among those who were reached successfully.

CONCLUSIONS

Improvement in immunization rates was seen in the short term but not the long term after contacting both the parent and adolescent. Although telephone interventions may be effective when rapid immunization is necessary, the difficulty in reaching parents and adolescents by phone highlights the importance of up-to-date contact information and a need to assess the effectiveness of alternative means of communication.

摘要

目的

确定通过联系父母或同时联系父母和青少年是否可以提高青少年的免疫接种率。

方法

将至少有 1 种 3 种免疫接种逾期 13 至 17 岁的青少年随机分配到(1)对照组(Control),(2)仅给父母/监护人打电话(Parent Only),或(3)给父母/监护人打电话和青少年(Parent/Adol)。在干预后 4 周和 1 年评估免疫记录。使用双侧 χ(2)检验和逻辑回归模型比较研究臂的免疫接种率。

结果

意向治疗分析显示,与对照组相比,Parent/Adol 组在 4 周时(调整后的优势比 2.27,95%置信区间 1.00-5.18)免疫接种率提高,但在 1 年时未提高。Parent Only 组的免疫接种率呈上升趋势(比值比 2.02,95%置信区间 0.89-4.56)。然而,干预组中的许多父母和青少年都无法进行电话联系。对实际电话联系影响的事后分析显示,在成功联系到的人群中,4 周和 1 年后的免疫接种率均有显著提高。

结论

在同时联系父母和青少年后,短期可以提高免疫接种率,但长期效果不明显。尽管电话干预在需要快速免疫接种时可能有效,但难以通过电话联系到父母和青少年突显了及时更新联系信息的重要性,并需要评估替代沟通方式的有效性。

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