Department of Dermatology, Toranomon Hospital, Tokyo, Japan.
Int J Dermatol. 2012 Sep;51(9):1068-73. doi: 10.1111/j.1365-4632.2011.05363.x.
Although basal cell carcinoma (BCC) is the most common type of skin cancer, the incidence of metastasis is exceedingly low.
Case presentation of a basal cell carcinoma arising on the dorsum of the foot with inguinal and pelvic lymph node metastases.
Case presentation with literature review.
On the basis of our review of Japanese literature, the risk factors for BCC metastasis are occurrence on the genitalia, diameter of more than 3 cm, deep invasion of tumor cells into extradermal structures, and infiltrative/morpheic histological type.
Although metastasis from BCC is extremely rare, the prognosis of metastatic BCC is often poor. Careful follow-up is recommended in cases with high risk factors.
基底细胞癌(BCC)虽是最常见的皮肤癌,但转移率极低。
报告一例发生于足部背侧、伴腹股沟和盆腔淋巴结转移的基底细胞癌。
病例报告并文献复习。
根据我们对日本文献的回顾,BCC 转移的危险因素包括发生于生殖器、直径大于 3cm、肿瘤细胞深度侵入表皮下结构以及浸润性/形态学组织学类型。
尽管 BCC 转移极为罕见,但转移性 BCC 的预后通常较差。对于具有高危因素的病例,建议密切随访。