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Spatial memory deficit resulting from ischemia-induced damage to the hippocampus is ameliorated by intra-hippocampal transplants of fetal hippocampal neurons.

作者信息

Onifer S M, Low W C

机构信息

Department of Physiology and Biophysics, Indiana University School of Medicine, Indianapolis 46202-5120.

出版信息

Prog Brain Res. 1990;82:359-66. doi: 10.1016/s0079-6123(08)62623-0.

DOI:10.1016/s0079-6123(08)62623-0
PMID:2290949
Abstract
摘要

相似文献

1
Spatial memory deficit resulting from ischemia-induced damage to the hippocampus is ameliorated by intra-hippocampal transplants of fetal hippocampal neurons.海马体缺血性损伤导致的空间记忆缺陷可通过海马内移植胎儿海马神经元得到改善。
Prog Brain Res. 1990;82:359-66. doi: 10.1016/s0079-6123(08)62623-0.
2
Cholinergic-rich transplants alleviate cognitive deficits in lesioned rats, but exacerbate response to cholinergic drugs.富含胆碱能的移植体可缓解受损大鼠的认知缺陷，但会加剧对胆碱能药物的反应。
Prog Brain Res. 1990;82:347-58. doi: 10.1016/s0079-6123(08)62622-9.
3
Transplantation of fetal hippocampus may prevent or produce behavioral recovery from hippocampal ablation and recovery persists after removal of the transplant.移植胎儿海马体可能预防或促使海马体切除后的行为恢复，并且在移除移植物后恢复仍会持续。
Prog Brain Res. 1990;82:367-76. doi: 10.1016/s0079-6123(08)62624-2.
4
Transplantation of cryopreserved fetal hippocampal cells into ischemic lesions in the adult rat hippocampus.将冷冻保存的胎鼠海马细胞移植到成年大鼠海马的缺血性损伤部位。
Cell Transplant. 1994;3 Suppl 1:S39-41. doi: 10.1177/096368979400301s15.
5
Functional integration of neurons in homotopic and heterotopic intra-cortical grafts with the host brain.
Prog Brain Res. 1990;82:287-300. doi: 10.1016/s0079-6123(08)62615-1.
6
Temporal pattern of synaptophysin expression in cryopreserved fetal hippocampal cells transplanted into ischemically damaged adult rat hippocampus.移植到缺血损伤成年大鼠海马体中的冷冻保存胎儿海马体细胞中突触素表达的时间模式。
Cell Transplant. 1995;4 Suppl 1:S9-11. doi: 10.1016/0963-6897(94)00073-s.
7
Development of fetal hippocampal grafts in intact and lesioned hippocampus.
Prog Neurobiol. 1996 Dec;50(5-6):597-653. doi: 10.1016/s0301-0082(96)00048-2.
8
Foetal grafts from hippocampal regio superior alleviate ischaemic-induced behavioural deficits.
Behav Brain Res. 1993 Dec 20;58(1-2):107-12. doi: 10.1016/0166-4328(93)90095-8.
9
Prolonged electrophysiological maturation of transplanted hippocampal neurons.
Brain Res. 1990 Aug 6;524(2):331-5. doi: 10.1016/0006-8993(90)90711-j.
10
Transplant-induced working memory deficits in hippocampectomized rats.海马切除大鼠移植诱导的工作记忆缺陷
Physiol Behav. 1993 Sep;54(3):579-87. doi: 10.1016/0031-9384(93)90253-c.

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J Comp Neurol. 2009 Jul 1;515(1):125-44. doi: 10.1002/cne.22038.
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Fetal hippocampal grafts containing CA3 cells restore host hippocampal glutamate decarboxylase-positive interneuron numbers in a rat model of temporal lobe epilepsy.在颞叶癫痫大鼠模型中，含有CA3细胞的胎儿海马移植可恢复宿主海马中谷氨酸脱羧酶阳性中间神经元的数量。
J Neurosci. 2000 Dec 1;20(23):8788-801. doi: 10.1523/JNEUROSCI.20-23-08788.2000.
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Hippocampal tissue transplants reverse lesion-induced spatial memory deficits in zebra finches (Taeniopygia guttata).海马组织移植可逆转斑胸草雀（Taeniopygia guttata）损伤诱导的空间记忆缺陷。
J Neurosci. 1997 May 15;17(10):3861-9. doi: 10.1523/JNEUROSCI.17-10-03861.1997.