肢端肥大症中的甲状腺结节。
Thyroid nodules in acromegaly.
作者信息
Rogozinski Amelia, Furioso Alejandra, Glikman Patricia, Junco Marcelo, Laudi Rosa, Reyes Adriana, Lowenstein Alicia
机构信息
División Endocrinología, Hospital J. M. Ramos Mejía, Buenos Aires, Argentina.
出版信息
Arq Bras Endocrinol Metabol. 2012 Jul;56(5):300-4. doi: 10.1590/s0004-27302012000500004.
OBJECTIVE
We made a prospective study evaluating the prevalence of thyroid nodular disease in acromegalic patients.
SUBJECTS AND METHODS
Thyroid ultrasound and ultrasound-guided fine needle aspiration biopsy were performed when nodules were detected. Nodules were characterized by cytology and histopathology.
RESULTS
We found high prevalence of nodular thyroid disorder, 23/34 (67%) in acromegalic patients. High risk and malignant cytology were significantly higher in acromegalic patients than in our non-acromegalic population (25% vs. 9%). Differentiated thyroid carcinoma was present in 11% of the acromegalic patients.
CONCLUSIONS
We strongly recommend periodic thyroid evaluation by ultrasound in patients with acromegaly. Fine needle aspiration biopsy should be performed in nodules larger than 10 mm, and in all suspicious nodules, regardless of the size.
目的
我们进行了一项前瞻性研究，以评估肢端肥大症患者甲状腺结节性疾病的患病率。
研究对象与方法
当检测到结节时，进行甲状腺超声检查及超声引导下细针穿刺活检。通过细胞学和组织病理学对结节进行特征描述。
结果
我们发现肢端肥大症患者甲状腺结节性疾病的患病率较高，34例中有23例（67%）患病。肢端肥大症患者中高风险和恶性细胞学特征的比例显著高于非肢端肥大症人群（25%对9%）。11%的肢端肥大症患者存在分化型甲状腺癌。
结论
我们强烈建议对肢端肥大症患者定期进行甲状腺超声检查。对于直径大于10毫米的结节以及所有可疑结节，无论大小，均应进行细针穿刺活检。
Zotero 插件