Diepgen T L, Stäbler A, Hornstein O P
Dermatologische Universitäts-Klinik Erlangen.
Z Hautkr. 1990 Oct;65(10):907-10.
In patients suffering from atopic dermatitis (AD), we often find intolerance reactions against wool, whereas irritation by synthetic fibers is still a matter of discussion. In a randomized clinical study on 55 patients with AD and 31 healthy controls, we investigated the irritative capacity of poncho-like shirts made of 4 different materials (A: cotton; B, C, D: synthetics of different fiber structure). The intensity of itching or discomfort due to repeated wearing of these shirts was evaluated by means of a point system (max.comfort = 10 points, max. discomfort = 1 point). Our study clearly showed that the irritative capacity of synthetic shirts is significantly higher in patients with AD, while cotton shirts were best tolerated. We also observed significant difference regarding the surface structure and diameter of the synthetic fibers under investigation.
在患有特应性皮炎（AD）的患者中，我们经常发现他们对羊毛存在不耐受反应，而合成纤维引起的刺激仍存在争议。在一项针对55例AD患者和31名健康对照的随机临床研究中，我们调查了由4种不同材料制成的雨披式衬衫的刺激能力（A：棉；B、C、D：不同纤维结构的合成材料）。通过评分系统评估因反复穿着这些衬衫而引起的瘙痒或不适程度（最大舒适度 = 10分，最大不适感 = 1分）。我们的研究清楚地表明，合成衬衫对AD患者的刺激能力明显更高，而棉质衬衫的耐受性最佳。我们还观察到所研究的合成纤维在表面结构和直径方面存在显著差异。
