State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China.
Environ Sci Technol. 2012 Sep 4;46(17):9745-52. doi: 10.1021/es302272a. Epub 2012 Aug 22.
Atmospheric particulate matter samples were collected from May 2010 to April 2011 in a rural e-waste area and in Guangzhou, South China, to estimate the lifetime inhalation cancer risk from exposure to parent polycyclic aromatic hydrocarbons (PAHs), high molecular weight PAHs (MW 302 PAHs), and halogenated PAHs (HPAHs). Seasonal variations in the PAH concentrations and profiles within and between the e-waste and urban areas indicated different PAH sources in the two areas. Benzo[b]fluoranthene, benzo[a]pyrene, dibenz[ah]anthracene, and dibenzo[al]pyrene made the most significant contribution to the inhalation cancer risk. MW 302 PAHs accounted for 18.0% of the total cancer risk in the e-waste area and 13.6% in the urban area, while HPAHs made a minor contribution (<0.1%) in both the areas. The number of lifetime excess lung cancers due to exposure to parent PAHs, MW 302 PAHs, and HPAHs ranged from 15.1 to 1198 per million people in the e-waste area and from 9.3 to 737 per million people in Guangzhou. PAH exposure accounted for 0.02 to 1.94% of the total lung cancer cases in Guangzhou. On average, the inhalation cancer risk in the e-waste area was 1.6 times higher than in the urban area. The e-waste dismantling activities in South China led to higher inhalation cancer risk due to PAH exposure than the urban area.
从 2010 年 5 月到 2011 年 4 月，在华南一个农村电子废物区和广州采集大气颗粒物样本，以评估接触母体多环芳烃 (PAHs)、高分子量 PAHs (MW 302 PAHs) 和卤代 PAHs (HPAHs) 导致的终生吸入性癌症风险。电子废物区和城区内和之间的 PAH 浓度和分布的季节性变化表明，这两个地区存在不同的 PAH 来源。苯并[b]荧蒽、苯并[a]芘、二苯并[a,h]蒽和二苯并[a,l]芘对吸入性癌症风险的贡献最大。MW 302 PAHs 占电子废物区总癌症风险的 18.0%，占城区总癌症风险的 13.6%，而 HPAHs 在这两个地区的贡献都较小（<0.1%）。由于接触母体 PAHs、MW 302 PAHs 和 HPAHs，电子废物区每百万人口中终生超额肺癌病例数为 15.1 至 1198 例，广州为 9.3 至 737 例。PAH 暴露占广州总肺癌病例的 0.02%至 1.94%。平均而言，电子废物区的吸入性癌症风险比城区高 1.6 倍。华南地区的电子废物拆解活动导致 PAH 暴露导致的吸入性癌症风险高于城区。
