Darby J E, Carr R A, Beazley L D
Department of Psychology, University of Western Australia, Nedlands.
Anat Embryol (Berl). 1990;182(5):487-92. doi: 10.1007/BF00178914.
We estimated cell numbers in the ganglion cell and inner nuclear layers of adult frog (Hyla moorei) retinae, examining normal animals and those with regenerated optic nerves. Analysis of sections stained with cresyl violet showed that cell numbers in a nasotemporal strip, which included the area centralis and visual streak, were comparable between sides for both these cellular layers in normal animals. In line with our previous observations, after optic nerve regeneration cell numbers in the ganglion cell layer had fallen by 35-43% compared to the unoperated sides. By contrast cell numbers remained similar for the inner nuclear layers on the two sides. We conclude that retrograde transneuronal degeneration had not taken place in the inner nuclear layer in response to ganglion cell death.
我们估计了成年青蛙（摩尔雨蛙）视网膜神经节细胞层和内核层中的细胞数量，研究了正常动物以及视神经再生的动物。对用甲酚紫染色的切片进行分析表明，在正常动物中，包含中央凹和视纹的鼻颞侧条带中这两个细胞层两侧的细胞数量相当。与我们之前的观察结果一致，视神经再生后，神经节细胞层中的细胞数量比未手术侧减少了35%-43%。相比之下，两侧内核层的细胞数量保持相似。我们得出结论，内核层并未因神经节细胞死亡而发生逆行跨神经元变性。
